Art

J-GLOBAL ID：200902171167675310   Reference number：00A0131621

A Chiral Synthesis of Four Stereoisomers of 1,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline, an Inducer of Parkinson-like Syndrome.

Parkinson様症候群の誘発物質,1,3-ジメチル-1,2,3,4-テトラヒドロイソキノリンの4立体異性体のキラル合成

Author (4)： TODA J (Showa Coll. Pharmaceutical Sci., Tokyo, JPN) ,  MATSUMOTO S (Showa Coll. Pharmaceutical Sci., Tokyo, JPN) ,  SAITOH T (Showa Coll. Pharmaceutical Sci., Tokyo, JPN) ,  SANO T (Showa Coll. Pharmaceutical Sci., Tokyo, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 48  Issue： 1  Page： 91-98  Publication year： Jan. 01, 2000 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,...

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JST classification (1)： Quinolines,isoquinolines  (CF07096H)

Substance index (20)： 1β,3β-Dimethyl-1,2,3,4-tetrahydroisoquinoline ,  1α,3β-Dimethyl-1,2,3,4-tetrahydroisoquinoline ,  1β,3α-Dimethyl-1,2,3,4-tetrahydroisoquinoline ,  1α,3α-Dimethyl-1,2,3,4-tetrahydroisoquinoline ,  (S)-1-(Phenylthio)-2-propanamine ,  (R)-1-(Phenylthio)-2-propanamine ,  (S)-N-Benzyl-1-(phenylthio)-2-propanamine ,  (R)-N-Benzyl-1-(phenylthio)-2-propanamine ,  N-Benzyl-N-[(S)-1-methyl-2-phenylsulfinylethyl]formamide ,  N-Benzyl-N-[(R)-1-methyl-2-phenylsulfinylethyl]formamide ,  (2S)-N-[(R)-1-Phenylethyl]-1-(phenylthio)-2-propanamine ,  (2S)-N-[(S)-1-Phenylethyl]-1-(phenylthio)-2-propanamine ,  (2R)-N-[(R)-1-Phenylethyl]-1-(phenylthio)-2-propanamine ,  (2R)-N-[(S)-1-Phenylethyl]-1-(phenylthio)-2-propanamine ,  N-[(R)-α-Methylbenzyl]-N-[(S)-1-methyl-2-phenylsulfinylethyl]formamide ,  N-[(S)-α-Methylbenzyl]-N-[(R)-1-methyl-2-phenylsulfinylethyl]formamide ,  N-[(S)-α-Methylbenzyl]-N-[(S)-1-methyl-2-phenylsulfinylethyl]formamide ,  N-[(R)-α-Methylbenzyl]-N-[(R)-1-methyl-2-phenylsulfinylethyl]formamide ,  3β-Methyl-1,2,3,4-tetrahydroisoquinoline ,  (R)-3-Methyl-1,2,3,4-tetrahydroisoquinoline

Reference (19)：

• NAGATSU, T. Neurosci. Res. 1997, 29, 99-111
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Terms in the title (7)： 症候群 ,  誘発 ,  物質 ,  ジメチル ,  テトラヒドロイソキノリン ,  立体異性体 ,  キラル