A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice.

KAWATE H; ITOH R; SAKUMI K; NAKABEPPU Y; IDE F; ISHIKAWA T; NODA T; NAWATA H; SEKIGUCHI M

Art

J-GLOBAL ID：200902171235119367 Reference number：00A0332651

A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice.

Mlh1遺伝子の単一対立遺伝子での欠陥はメチルトランスフェラーゼ欠損マウスでアルキル化発癌物質の致死作用と腫よう発生作用の解離を起こす

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Material：
Volume： 21 Issue： 2 Page： 301-305 Publication year： Feb. 2000
JST Material Number： B0997C ISSN： 0143-3334 CODEN： CRNGDP Document type： Article
Article type：原著論文 Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Carcinogenic mechanisms and factors , Molecular genetics in general

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