Art

J-GLOBAL ID：200902176034460542   Reference number：02A0511753

Inhibition of the Association of Proteoglycans with Cultured Vascular Endothelial Cell Layers by Calcium and Sodium Spirulan.

カルシウム及びナトリウムスピルランによる培養血管内皮細胞層へのプロテオグリカン結合阻害

Author (6)： KAJI T (Hokuriku Univ., Kanazawa, JPN) ,  SHIMADA S (Hokuriku Univ., Kanazawa, JPN) ,  YAMAMOTO C (Hokuriku Univ., Kanazawa, JPN) ,  FUJIWARA Y (Hokuriku Univ., Kanazawa, JPN) ,  LEE J-B (Toyama Medical and Pharmaceutical Univ., Toyama, JPN) ,  HAYASHI T (Toyama Medical and Pharmaceutical Univ., Toyama, JPN)
Material： Journal of Health Science  (J Health Sci)
Volume： 48  Issue： 3  Page： 250-255  Publication year： Jun. 01, 2002 
JST Material Number： S0030A  ISSN： 1344-9702  CODEN： JHSCFD  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pharmacological action ,...
Semi thesaurus term： カルシウムスピルラン ,...

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JST classification (1)： Drugs acting on metabolism in general  (GW13010F)

Reference (24)：

• 1) Hayashi, T., Hayashi, K., Maeda, M. and Kojima, I. (1996) Calcium spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina platensis. J. Nat. Prod., 59, 83-87.
• 2) Hayashi, K., Hayashi, T. and Kojima, I. (1996) A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities. AIDS Res. Hum. Retroviruses, 12, 1463-1471.
• 3) Lee, J. B., Hayashi, T., Hayashi, K., Sankawa, U., Maeda, M., Nemoto, T. and Nakanishi, H. (1998) Further purification and structural analysis of calcium spirulan from Spirulina platensis. J. Nat. Prod., 61, 1101-1104.
• 4) Lee, J. B., Hayashi, T., Hayashi, K. and Sankawa, U. (2000) Structural analysis of calcium spirulan (Ca-SP)-derived oligosaccharides using electrospray ionization mass spectrometry. J. Nat. Prod., 63, 136-138.
• 5) Hayakawa, Y., Hayashi, T., Hayashi, K., Hayashi, T., Ozawa, T., Niiya, K. and Sakuragawa, N. (1996) Heparin cofactor II-dependent antithrombin activity of calcium spirulan. Blood Coagul. Fibrinolysis, 7, 554-560.

Terms in the title (5)： カルシウム ,  培養 ,  血管内皮細胞 ,  プロテオグリカン ,  阻害