Art

J-GLOBAL ID：200902209919613465   Reference number：09A0913111

Binding affinity of full-length and extracellular domains of recombinant human (pro)renin receptor to human renin when expressed in the fat body and hemolymph of silkworm larvae

カイコ幼生の脂肪体や血リンパに発現させた組み換えヒト(プロ)レニン受容体の完全長および細胞外ドメインのヒトレニンに対する結合親和性

Author (5)： DU Dongning (Lab. of Biotechnology, Integrated Bioscience Section, Graduate School of Sci. and Technol., Shizuoka Univ., 836 Ohya ...) ,  KATO Tatsuya (Lab. of Biotechnology, Fac. of Agriculture, Shizuoka Univ., 836 Ohya, Suruga-ku, Shizuoka 422-8529, JPN) ,  SUZUKI Fumiaki (Lab. of Animal Biochemistry, Fac. of Applied Biological Sciences, Gifu Univ., 1-1 Yanagido, Gifu 501-1193, JPN) ,  PARK Enoch Y. (Lab. of Biotechnology, Integrated Bioscience Section, Graduate School of Sci. and Technol., Shizuoka Univ., 836 Ohya ...) ,  PARK Enoch Y. (Lab. of Biotechnology, Fac. of Agriculture, Shizuoka Univ., 836 Ohya, Suruga-ku, Shizuoka 422-8529, JPN)
Material： Journal of Bioscience and Bioengineering
Volume： 108  Issue： 4  Page： 304-309  Publication year： Oct. 2009 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *silkworm ,...
Semi thesaurus term： *renin receptor ,...

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JST classification (2)： Enzyme in general  (EB09010D) ,  Receptors on cell membrane  (EF04030C)

Reference (18)：

• NGUYEN, G. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J. Clin. Invest. 2002, 109, 1417-1427
• SUZUKI, F. Human prorenin has "Gate and Handle" regions for its non-proteolytic activation. J. Biol. Chem. 2003, 278, 22217-22222
• ICHIHARA, A. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J. Clin. Invest. 2004, 114, 1128-1135
• PRESCOTT, G. Tissue activity of circulating prorenin. Am. J. Hypertension. 2002, 15, 280-285
• BURCKLE, C. A. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension. 2006, 47, 552-556

Terms in the title (10)： カイコ ,  幼生 ,  脂肪体 ,  血リンパ ,  発現 ,  組み換え ,  ヒト ,  レニン受容体 ,  細胞外ドメイン ,  結合親和性