Art

J-GLOBAL ID：200902230923582662   Reference number：09A0116437

Thiazolidinediones inhibit REG Iα gene transcription in gastrointestinal cancer cells

チアゾリジンジオンは胃腸癌細胞におけるREG Iα遺伝子転写を阻害する

Author (16)： YAMAUCHI Akiyo (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  YAMAUCHI Akiyo (Lab. of Molecular Genetics, Tohoku Univ. Graduate School of Pharmaceutical Sciences, Sendai 980-8578, JPN) ,  YAMAUCHI Akiyo (Dep. of Biochemistry, Nara Medical Univ., Kashihara 634-8521, JPN) ,  TAKAHASHI Iwao (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  TAKASAWA Shin (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  TAKASAWA Shin (Dep. of Biochemistry, Nara Medical Univ., Kashihara 634-8521, JPN) ,  NATA Koji (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  NOGUCHI Naoya (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  IKEDA Takayuki (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  YOSHIKAWA Takeo (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  SHERVANI Nausheen J. (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  SUZUKI Iwao (Lab. of Molecular Genetics, Tohoku Univ. Graduate School of Pharmaceutical Sciences, Sendai 980-8578, JPN) ,  URUNO Akira (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  UNNO Michiaki (Dep. of Surgery, Tohoku Univ. Graduate School of Medicine, Sendai 980-8574, JPN) ,  OKAMOTO Hiroshi (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...) ,  SUGAWARA Akira (Dep. of Advanced Biological Sciences for Regeneration (Kotobiken Medical Laboratories), Tohoku Univ. Graduate School ...)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 379  Issue： 3  Page： 743-748  Publication year： Feb. 13, 2009 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,  *stomach tumor ,  *intestinal tumor ,  tumor cell ,  *gene ,  *transcription (genetics) ,  growth factor ,  gene expression ,  PPAR gamma ,  Cell Proliferation ,  mRNA ,  promoter (genetics) ,  antifungal drug ,  protein synthesis ,  antitumor drug ,  acid imide ,  alicyclic ketone ,  secondary alcohol ,  hydroxy ketone ,  PPAR-gamma Agonists ,  *Reg gene ,  molecular genetic phenomenon
Semi thesaurus term： PPAR gamma agonist ,  *Stomach cancer ,  Cancer cell ,  anticancer agent ,  *regeneration gene ,  *Bowel cancer

JST classification (4)： Basic oncology in general  (GE02010R) ,  Gene expression  (EC02040Q) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic medicine on digestive system  (GH01020E)

Substance index (2)： Cycloheximide ,  2,4-Thiazolidinedione

Terms in the title (4)： チアゾリジンジオン ,  癌細胞 ,  遺伝子転写 ,  阻害