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J-GLOBAL ID：200902240034421342   Reference number：04A0400589

Novel Insertional Mutation in the Bone Morphogenetic Protein Receptor Type II Associated With Sporadic Primary Pulmonary Hypertension

散発性原発性肺高血圧と関係した骨形態形成蛋白質受容体II型における新しい挿入変異

Author (9)： SUGIYAMA S (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  HIROTA H (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  YOSHIDA M (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  TAKEMURA Y (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  NAKAOKA Y (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  OSHIMA Y (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  TERAI K (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  IZUMI M (Osaka Univ. Graduate School of Medicine, Suita, JPN) ,  FUJIO Y (Osaka Univ. Graduate School of Medicine, Suita, JPN)
Material： Circulation Journal  (Circ J)
Volume： 68  Issue： 6  Page： 592-594  Publication year： Jun. 2004 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： bone morphogenetic protein

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JST classification (1)： Cardiovascular system diseases  (GJ03000C)

Reference (11)：

• 1. D'Alonzo GE, Barst RJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 1991; 115: 343-349.
• 2. Shiomi T, Guilleminault C, Sasanabe R, Oki Y, Hasegawa R, Otake K, et al. Primary pulmonary hypertension with central sleep apnea: Sudden death after bilevel positive airway pressure therapy. Jpn Circ J 2000; 64: 723-726.
• 3. Rich S, Dantzker DR, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, et al. Primary pulmonary hypertension: A national prospective study. Ann Intern Med 1987; 107: 216-223.
• 4. Barst RJ, Rubin LJ, Long WA, McGoon MD, Rich S, Badesch DB, et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension: The Primary Pulmonary Hypertension Study Group. N Engl J Med 1996; 334: 296-302.
• 5. Kusano KF, Date H, Fujio H, Miyaji K, Matsubara H, Nagahiro I, et al. Recovery of cardiac function after living-donor lung transplantation in a patient with primary pulmonary hypertension. Circ J 2002; 66: 294-296.

Terms in the title (4)： 原発性肺高血圧 ,  骨形態形成蛋白質 ,  受容体 ,  挿入変異