Art

J-GLOBAL ID：200902252077418050   Reference number：05A0111953

Fungal Phenalenones Inhibit HIV-1 Integrase

糸状菌フェナレノンはHIV-1インテグラーゼを阻害する

Author (9)： SHIOMI K (Kitasato Univ., Tokyo, JPN) ,  MATSUI R (Kitasato Univ., Tokyo, JPN) ,  ISOZAKI M (Kitasato Univ., Tokyo, JPN) ,  YAMAGUCHI Y (Kitasato Inst., Tokyo, JPN) ,  MASUMA R (Kitasato Inst., Tokyo, JPN) ,  TOMODA H (Kitasato Inst., Tokyo, JPN) ,  CHIBA T (National Inst. Infectious Diseases, Tokyo, JPN) ,  YAN H (National Inst. Infectious Diseases, Tokyo, JPN) ,  KITAMURA Y (Univ. Tokyo, Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 58  Issue： 1  Page： 65-68  Publication year： Jan. 25, 2005 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *mold fungi ,...
Semi thesaurus term： IC50 ,...

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JST classification (2)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Metabolism and nutrition  (EG03054K)

Substance index (3)： Atrovenetinone methyl acetal ,  Funalenone ,  Erabulenol B

Reference (21)：

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• PALELLA, FJ Jr. Declining morbidity and morality among patients with advanced human immunodeficiency virus infection. N Engl J Med. 1998, 338, 853-860
• DEEKS, SG. Treatment of antiretroviral-drug-resistant HIV-1 infection. Lancet. 2003, 362, 2002-2011
• MATSUZAKI, K. Isochromophilones I and II, novel inhibitors against gp120-CD4 binding produced by Penicillium multicolor FO-2338. I. Screening, taxonomy, fermentation, isolation and biological activity. J Antibiot. 1995, 48, 703-707
• TANAKA, H. Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. 1. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot. 1997, 50, 58-65

Terms in the title (4)： 糸状菌 ,  HIV-1 ,  インテグラーゼ ,  阻害