Art

J-GLOBAL ID：200902255069476970   Reference number：04A0375339

Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells

CD3/CD28刺激したナイーブT細胞における活性化cAMP/cAMP依存性蛋白質キナーゼ(蛋白質キナーゼA)経路によるIL4産生の上方制御

Author (9)： TOKOYODA K (Osaka Univ., Osaka, JPN) ,  TSUJIKAWA K (Osaka Univ., Osaka, JPN) ,  MATSUSHITA H (Osaka Univ., Osaka, JPN) ,  ONO Y (Osaka Univ., Osaka, JPN) ,  HAYASHI T (Osaka Univ., Osaka, JPN) ,  HARADA Y (Tokyo Univ. Sci., Chiba, JPN) ,  ABE R (Tokyo Univ. Sci., Chiba, JPN) ,  KUBO M (Tokyo Univ. Sci., Chiba, JPN) ,  YAMAMOTO H (Osaka Univ., Osaka, JPN)
Material： International Immunology  (Int Immunol)
Volume： 16  Issue： 5  Page： 643-653  Publication year： May. 2004 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *interleukin 4 ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (54)：

• SCHWARTZ, R. H. A cell culture model for T lymphocyte clonal anergy. Science. 1990, 248, 1349
• JUNE, C. H. The B7 and CD28 receptor families. Immunol. Today. 1994, 15, 321
• LINSLEY, P. S. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 1993, 11, 191
• SCHWARTZ, R. H. Co-stimulation of T lymphocytes : the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell. 1992, 71, 1065
• GIMMI, C. D. Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 co-stimulation. Proc. Natl Acad. Sci. USA. 1993, 90, 6586

Terms in the title (11)： CD3 ,  CD28 ,  刺激 ,  ナイーブT細胞 ,  活性化 ,  cAMP ,  cAMP依存性蛋白質キナーゼ ,  蛋白質キナーゼA ,  経路 ,  IL4 ,  上方制御