Art

J-GLOBAL ID：200902255122407330   Reference number：09A0599165

Characterization of antioxidant protection of cultured neural progenitor cells (NPC) against methylmercury (MeHg) toxicity

メチル水銀(MeHg)毒性に対する培養神経前駆体細胞(NPC)の抗酸化保護の性質

Author (9)： WATANABE Jun (Dep. of Anatomy, School of Medicine, Showa Univ.) ,  WATANABE Jun (Dep. of Biology, Fac. of Education and Integrated Arts and Sciences, Waseda Univ.) ,  NAKAMACHI Tomoya (Dep. of Anatomy, School of Medicine, Showa Univ.) ,  OGAWA Tetsuo (Anti-aging Funded Res. Labs, School of Medicine, Showa Univ.) ,  NAGANUMA Akira (Lab. of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku Univ.) ,  NAKAMURA Masahisa (Dep. of Biology, Fac. of Education and Integrated Arts and Sciences, Waseda Univ.) ,  SHIODA Seiji (Dep. of Anatomy, School of Medicine, Showa Univ.) ,  NAKAJO Sigeo (Dep. of Anatomy, School of Medicine, Showa Univ.) ,  NAKAJO Sigeo (Lab. of Biochemistry, Yokohama Coll. of Pharmacy)
Material： Journal of Toxicological Sciences  (日本毒性学会学術年会プログラム・要旨集)
Volume： 34  Issue： 3  Page： 315-325 (J-STAGE)  Publication year： 2009 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *organomercury compound ,...
Semi thesaurus term： *Neurobehavioral Manifestations ,...

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JST classification (3)： Basic neurology  (GN01020W) ,  Antidotes  (GZ04020B) ,  Mercury and its compounds  (SB05023Z)

Substance index (5)： Methylmercury ,  Glutathione ,  Buthionine sulfoximine ,  Acetylcysteine ,  alpha-Tocopherol

Reference (54)：

• AHLBOM, E. Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death. Proc. Natl. Acad. Sci. USA. 2000, 97, 14726-14730
• AHMAD, S. Oxidative stress from environmental pollutants. Arch. Insect. Biochem. Physiol. 1995, 29, 135-157
• ALLY, A. Interaction of methylmercury chloride with cellular energetics and related processes. Toxicol. Appl. Pharmacol. 1984, 76, 207-218
• AMIN-ZAKI, L. Perinatal methylmercury poisoning in Iraq. Am. J. Dis. Child. 1976, 130, 1070-1076
• ASCHNER, M. Neurotoxic mechanisms of fish-borne methylmercury. Environ. Toxicol. Pharmacol. 2002, 12, 101-104

Terms in the title (8)： メチル水銀 ,  毒性 ,  培養 ,  神経 ,  前駆体細胞 ,  NPC ,  酸化 ,  性質