Art

J-GLOBAL ID：200902255282113791   Reference number：09A0894612

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in Apc^Min/+ mice with natural ligands

アリール炭化水素受容体は天然リガンドによりApc^Min/+マウスにおける腸発癌を抑制する

Author (18)： KAWAJIRI Kaname (Saitama Cancer Center, Saitama, JPN) ,  KOBAYASHI Yasuhito (Saitama Cancer Center, Saitama, JPN) ,  OHTAKE Fumiaki (JST-ERATO, Saitama, JPN) ,  OHTAKE Fumiaki (Univ. Tokyo, Tokyo, JPN) ,  IKUTA Togo (Saitama Cancer Center, Saitama, JPN) ,  MATSUSHIMA Yoshibumi (Saitama Cancer Center, Saitama, JPN) ,  MIMURA Junsei (Univ. Tsukuba, Ibaraki, JPN) ,  PETTERSSON Sven (Karolinska Inst., Stockholm, SWE) ,  POLLENZ Richard S. (Univ. South Florida, FL) ,  SAKAKI Toshiyuki (Toyama Prefectural Univ., Toyama, JPN) ,  HIROKAWA Takatsugu (National Inst. Advanced Industrial Sci. and Technol., Tokyo, JPN) ,  AKIYAMA Tetsu (Univ. Tokyo, Tokyo, JPN) ,  KUROSUMI Masafumi (Saitama Cancer Center, Saitama, JPN) ,  POELLINGER Lorenz (Karolinska Inst., Stockholm, SWE) ,  KATO Shigeaki (JST-ERATO, Saitama, JPN) ,  KATO Shigeaki (Univ. Tokyo, Tokyo, JPN) ,  FUJII-KURIYAMA Yoshiaki (JST-ERATO, Saitama, JPN) ,  FUJII-KURIYAMA Yoshiaki (Univ. Tsukuba, Ibaraki, JPN)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 106  Issue： 32  Page： 13481-13486  Publication year： Aug. 11, 2009 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Ah receptor ,  Mus musculus ,  *Carcinogenesis ,  *antitumor action ,  *tumor suppressor protein ,  molecule ,  peptide synthase ,  transcription factor ,  catenin ,  glucosinolate ,  *colonic neoplasm ,  *rectal neoplasm ,  enteric microbe ,  *nitrogen heterocyclic compound ,  *polynuclear aromatic compound ,  amino acid ,  primary amine ,  Ligands ,  Wnt Signaling Pathway ,  Activating Transcription Factors ,  beta Catenin ,  enteric bacteria ,  Genetic Variation ,  Signal Transduction ,  *cancer chemopreventive effect ,  *Adenomatous Polyposis Coli Protein ,  Ubiquitin-Protein Ligases ,  *Indoles ,  Myomorpha ,  Proteins
Semi thesaurus term： genetic variation ,  cellular signal transduction ,  *Receptors, Aryl Hydrocarbon ,  *cancer chemopreventive effect ,  *APC protein ,  Wnt signaling ,  E3 ubiquitin ligase ,  *colorectal cancer ,  *Indoles

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Receptors on cell membrane  (EF04030C)

Substance index (1)： Tryptophan

Terms in the title (5)： アリール炭化水素受容体 ,  リガンド ,  マウス ,  腸 ,  発癌