Art

J-GLOBAL ID：200902272289234677   Reference number：09A0193578

Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice

Keap1/Nrf2システムはKeap1遺伝子ノックアウトマウス研究で明らかにされたように神経細胞生存性を調節する

Author (6)： SATOH Takumi (Dep. of Welfare Engineering, Fac. of Engineering, Iwate Univ., Ueda 4-3-5, Morioka, Iwate 020-8551, JPN) ,  HARADA Nobuhiko (Dep. of Stress Response Sci., Hirosaki Univ. Graduate School of Medicine, Hirosaki, Aomori 036-8562, JPN) ,  HOSOYA Tomonori (Dep. of Stress Response Sci., Hirosaki Univ. Graduate School of Medicine, Hirosaki, Aomori 036-8562, JPN) ,  TOHYAMA Koujiro (Center for EM and Bio-Imaging Res., Iwate Medical Univ., Morioka, JPN) ,  YAMAMOTO Masayuki (Dep. of Medical Biochemistry, Tohoku Univ. Graduate School of Medicine, 2-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, JPN) ,  ITOH Ken (Dep. of Stress Response Sci., Hirosaki Univ. Graduate School of Medicine, Hirosaki, Aomori 036-8562, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 380  Issue： 2  Page： 298-302  Publication year： Mar. 06, 2009 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： knockout mouse ,  *actin binding protein ,  *metalloprotein ,  DNA binding protein ,  transcription factor ,  neuron ,  oxidative stress ,  *protective action ,  *pharmacological action ,  electrophilic reagent ,  Central Nervous System ,  cerebral cortex ,  gene expression ,  intracellular transport ,  electrophilic reaction ,  *Keap1 protein ,  NF-E2-Related Factor 2 ,  Cell Survival ,  *neurocyte protective effect ,  nuclear translocation ,  laboratory animal ,  Mus musculus ,  cortex ,  telencephalon ,  molecular genetic phenomenon
Semi thesaurus term： *Keap1 ,  Nrf2 ,  細胞生存性 ,  *neuroprotective action ,  nuclear localization

JST classification (2)： Function of cell components  (EF03060C) ,  Central nervous system  (EJ12030F)

Terms in the title (7)： Keap1 ,  NRF2 ,  遺伝子ノックアウトマウス ,  研究 ,  神経 ,  細胞生存性 ,  調節