Art

J-GLOBAL ID：200902278012972970   Reference number：08A0736478

Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations

遺伝学的解析はA:T変異を形成するための胚中心B細胞の固有の特性が明らかとなる

Author (14)： OUCHIDA Rika (Lab. for Immune Diversity, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., 1-7-22 Suehiro-cho, Tsurumi ...) ,  UKAI Akiko (Lab. for Immune Diversity, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., 1-7-22 Suehiro-cho, Tsurumi ...) ,  MORI Hiromi (Lab. for Immune Diversity, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., 1-7-22 Suehiro-cho, Tsurumi ...) ,  KAWAMURA Kiyoko (Div. of Pathology, Chiba Cancer Center Res. Inst., Chiba 260-8717, JPN) ,  DOLLE Martijn E.T. (National Inst. of Public Health and Environment, Bilthoven, NLD) ,  TAGAWA Masatoshi (Div. of Pathology, Chiba Cancer Center Res. Inst., Chiba 260-8717, JPN) ,  SAKAMOTO Akemi (Dep. of Developmental Genetics, Graduate School of Medicine, Chiba Univ., Chiba 260-8670, JPN) ,  TOKUHISA Takeshi (Dep. of Developmental Genetics, Graduate School of Medicine, Chiba Univ., Chiba 260-8670, JPN) ,  YOKOSUKA Tadashi (Lab. for Cell Signaling, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., Yokohama 230-0045, JPN) ,  SAITO Takashi (Lab. for Cell Signaling, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., Yokohama 230-0045, JPN) ,  YOKOI Masayuki (Graduate School of Frontier Biosciences, Osaka Univ., and SORST, JST, 1-3 Yamada-oka, Suita, Osaka 565-0871, JPN) ,  HANAOKA Fumio (Graduate School of Frontier Biosciences, Osaka Univ., and SORST, JST, 1-3 Yamada-oka, Suita, Osaka 565-0871, JPN) ,  VIJG Jan (Buck Inst. for Age Res., 8001 Redwood Boulevard, Novato, CA 94945, USA) ,  WANG Ji-yang (Lab. for Immune Diversity, Res. Center for Allergy and Immunology, RIKEN Yokohama Inst., 1-7-22 Suehiro-cho, Tsurumi ...)
Material： DNA Repair
Volume： 7  Issue： 8  Page： 1392-1398  Publication year： Aug. 02, 2008 
JST Material Number： W1339A  ISSN： 1568-7864  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Point Mutation ,  *immunoglobulin gene ,  *Cytidine Deaminase ,  DNA lesion ,  *mismatch repair ,  transgenic mouse ,  lymph node ,  DNA polymerase ,  Substrate Specificity ,  antibody formation ,  *B cell ,  DNA polymerase eta ,  Germinal Center ,  *GC B cell ,  Base Pair Mismatch ,  base pair
Semi thesaurus term： mismatched base pair ,  *B lymphocyte

JST classification (2)： Molecular genetics in general  (EC02010J) ,  Immunological reaction in general  (ED03010T)

Terms in the title (5)： 遺伝学 ,  解析 ,  変異 ,  胚中心B細胞 ,  固有