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J-GLOBAL ID：200902279584950583   Reference number：06A0040944

Total Synthesis of (+)-Batzelladine A and (-)-Batzelladine D, and Identification of Their Target Protein

(+)-バツェラジンAおよび(-)-バツェラジンDの全合成ならびにその標的蛋白質の同定

Author (9)： SHIMOKAWA Jun (Univ. Tokyo, Tokyo, JPN) ,  ISHIWATA Takanori (Inst. Physical and Chemical Res., Saitama, JPN) ,  SHIRAI Koji (Tokyo Univ. Agriculture and Technol., Tokyo, JPN) ,  KOSHINO Hiroyuki (Inst. Physical and Chemical Res., Saitama, JPN) ,  TANATANI Aya (Univ. Tokyo, Tokyo, JPN) ,  NAKATA Tadashi (Inst. Physical and Chemical Res., Saitama, JPN) ,  NAKATA Tadashi (Tokyo Univ. Sci., Tokyo, JPN) ,  HASHIMOTO Yuichi (Univ. Tokyo, Tokyo, JPN) ,  NAGASAWA Kazuo (Tokyo Univ. Agriculture and Technol., Tokyo, JPN)
Material： Chemistry - European Journal  (Chem Eur J)
Volume： 11  Issue： 23  Page： 6878-6888  Publication year： Nov. 18, 2005 
JST Material Number： W0744A  ISSN： 0947-6539  CODEN： CEUJED  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *antiviral action ,...

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JST classification (2)： Alkaloids  (CF10030D) ,  Basic research of antiviral drugs  (GW17040O)

Substance index (7)： Batzelladine A ,  Batzelladine D ,  4-[2,3-Bis(tert-butoxycarbonyl)guanidino]-1-butanol ,  (3R,4aβ)-1-(Benzyloxycarbonylimino)-2-(benzyloxycarbonyl)-3α-methyl-7β-[(S)-2-(tert-butyldimethylsiloxy)undecyl]octahydropyrrolo[1,2-c]pyrimidine-4α-carboxylic acid ,  (3R,4aβ)-1-(tert-Butyloxycarbonylimino)-2-(tert-butyloxycarbonyl)-3α-[9-(4-methoxybenzyloxy)nonyl]octahydropyrrolo[1,2-c]pyrimidine-4α-methanol ,  (3R)-1-(tert-Butyloxycarbonylimino)-2-(tert-butyloxycarbonyl)-3-[9-(4-methoxybenzyloxy)nonyl]-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbaldehyde ,  (3R)-1-[(tert-Butoxycarbonyl)imino]-3α-(9-hydroxynonyl)-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-2,4-dicarboxylic acid 2-tert-butyl 4-[4-[2,3-bis(tert-butoxycarbonyl)guanidino]butyl] ester

Terms in the title (5)： バツェラジンA ,  バツェラジンD ,  全合成 ,  標的蛋白質 ,  同定