Art

J-GLOBAL ID：200902282044891317   Reference number：06A0395721

An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway

喘息および関連表現型とTLRシグナリング経路の負のレギュレーター分子の多型性との相関研究

Author (19)： NAKASHIMA Kazuko (RIKEN, Kanagawa, JPN) ,  NAKASHIMA Kazuko (Kyoto Univ. School of Public Health, Kyoto, JPN) ,  HIROTA Tomomitsu (RIKEN, Kanagawa, JPN) ,  HIROTA Tomomitsu (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  OBARA Kazuhiko (RIKEN, Kanagawa, JPN) ,  SHIMIZU Makiko (RIKEN, Kanagawa, JPN) ,  JODO Aya (RIKEN, Kanagawa, JPN) ,  KAMEDA Makoto (Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Osaka, JPN) ,  DOI Satoru (Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Osaka, JPN) ,  FUJITA Kimie (Univ. Shiga Prefecture, Shiga, JPN) ,  SHIRAKAWA Taro (Kyoto Univ. School of Public Health, Kyoto, JPN) ,  ENOMOTO Tadao (Japanese Red Cross Soc., Wakayama, JPN) ,  KISHI Fumio (Kagoshima Univ. Graduate School of Medical and Dental Sci., Kagoshima, JPN) ,  YOSHIHARA Shigemi (Dokkyo Univ. School of Medicine, JPN) ,  MATSUMOTO Kenji (National Res. Inst. Child Health & Dev., Tokyo, JPN) ,  SAITO Hirohisa (National Res. Inst. Child Health & Dev., Tokyo, JPN) ,  SUZUKI Yoichi (Chiba Univ., Chiba, JPN) ,  NAKAMURA Yusuke (Univ. Tokyo, Tokyo, JPN) ,  TAMARI Mayumi (RIKEN, Kanagawa, JPN)
Material： Journal of Human Genetics  (J Hum Genet)
Volume： 51  Issue： 4  Page： 284-291  Publication year： 2006 
JST Material Number： Z0756A  ISSN： 1434-5161  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (2)： Structure and chemistry of genes  (EC02020U) ,  Respiratory system diseases  (GI03000Z)

Reference (26)：

• AKIRA, S. Toll-like receptor signalling. Nat Rev Immunol. 2004, 4, 499-511
• BASU, S. Toll-like receptors : function and roles in lung disease. Am J Physiol Lung Cell Mol Physiol. 2004, 286, L887-L892
• BRAUN-FAHRLANDER, C. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med. 2002, 347, 869-877
• COOK, DN. Toll-like receptors in the pathogenesis of human disease. Nat Immunol. 2004, 5, 975-979
• EDER, W. Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol. 2004, 113, 482-488

Terms in the title (10)： 喘息 ,  表現型 ,  TLR ,  シグナリング ,  経路 ,  レギュレーター ,  分子 ,  多型性 ,  相関 ,  研究