Art

J-GLOBAL ID：200902282913495273   Reference number：09A0850422

The use of a mutant TNF-α as a vaccine adjuvant for the induction of mucosal immune responses

粘膜免疫応答を誘導するためのワクチンアジュバントとしての変異型TNF-αの使用

Author (27)： KAYAMURO Hiroyuki (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  KAYAMURO Hiroyuki (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  ABE Yasuhiro (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  YOSHIOKA Yasuo (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  YOSHIOKA Yasuo (The Center for Advanced Medical Engineering and Informatics, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  KATAYAMA Kazufumi (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  KATAYAMA Kazufumi (Dep. of Allergy and Immunology, The Tokyo Metropolitan Inst. of Medical Sci., 3-18-22, Honkomagome, Bunkyo-ku, Tokyo ...) ,  NOMURA Tetsuya (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  NOMURA Tetsuya (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  YOSHIDA Tokuyuki (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  YOSHIDA Tokuyuki (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  YAMASHITA Kohei (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  YAMASHITA Kohei (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  YOSHIKAWA Tomoaki (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  YOSHIKAWA Tomoaki (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  KAWAI Yuichi (Fac. of Pharmaceutical Sciences, Kobe-Gakuin Univ., 1-1-3, Minatojima, Chuo-ku, Kobe 650-8586, JPN) ,  MAYUMI Tadanori (Fac. of Pharmaceutical Sciences, Kobe-Gakuin Univ., 1-1-3, Minatojima, Chuo-ku, Kobe 650-8586, JPN) ,  HIROI Takachika (Dep. of Allergy and Immunology, The Tokyo Metropolitan Inst. of Medical Sci., 3-18-22, Honkomagome, Bunkyo-ku, Tokyo ...) ,  ITOH Norio (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  NAGANO Kazuya (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  KAMADA Haruhiko (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  KAMADA Haruhiko (The Center for Advanced Medical Engineering and Informatics, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  TSUNODA Shin-ichi (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  TSUNODA Shin-ichi (The Center for Advanced Medical Engineering and Informatics, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  TSUTSUMI Yasuo (Lab. of Pharmaceutical Proteomics, National Inst. of Biomedical Innovation (NiBio), 7-6-8 Saito-Asagi, Ibaraki ...) ,  TSUTSUMI Yasuo (Graduate School of Pharmaceutical Sciences, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN) ,  TSUTSUMI Yasuo (The Center for Advanced Medical Engineering and Informatics, Osaka Univ., 1-6, Yamadaoka, Suita, Osaka 565-0871, JPN)
Material： Biomaterials
Volume： 30  Issue： 29  Page： 5869-5876  Publication year： Oct. 2009 
JST Material Number： C0964B  ISSN： 0142-9612  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *TNF alpha ,  vaccine ,  *adjuvant ,  biological activity ,  *mucosal immunity ,  Mus musculus ,  intranasal administration ,  *intranasal immunization ,  Immunomodulation ,  Myomorpha
Semi thesaurus term： immune regulation

JST classification (2)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Cytokines  (EB08090G)

Terms in the title (5)： 粘膜免疫応答 ,  誘導 ,  ワクチンアジュバント ,  変異型 ,  TNF-α