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J-GLOBAL ID：200902295674045524   Reference number：04A0026903

Formation of Two 4-Imidazolylmethylphosphonium Salts and their Synthetic Studies Toward Histamine H₃-Ligands

2種の4-イミダゾリルメチルホスホニウム塩の生成とそれらを利用したヒスタミン-H₃-リガンドの合成研究

Author (9)： HARUSAWA S (Osaka Univ. Pharmaceutical Sci., Osaka, JPN) ,  KAWAMURA M (Osaka Univ. Pharmaceutical Sci., Osaka, JPN) ,  KOYABU S (Osaka Univ. Pharmaceutical Sci., Osaka, JPN) ,  HOSOKAWA T (Osaka Univ. Pharmaceutical Sci., Osaka, JPN) ,  ARAKI L (Osaka Univ. Pharmaceutical Sci., Osaka, JPN) ,  SAKAMOTO Y (AZWELL, Inc., Osaka, JPN) ,  HASHIMOTO T (Osaka Univ., Osaka, JPN) ,  YAMAMOTO Y (Osaka Univ., Osaka, JPN) ,  YAMATODANI A (Osaka Univ., Osaka, JPN)
Material： Synthesis  (Journal of Synthetic Organic Chemistry)
Issue： 18  Page： 2844-2850  Publication year： Dec. 18, 2003 
JST Material Number： D0738A  ISSN： 0039-7881  CODEN： SYNTBF  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： Wittig reaction

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JST classification (4)： Organop phosphorus compounds  (CF08040N) ,  Imidazoles  (CF07083X) ,  Synthesis of drugs  (GV01030F) ,  Receptors on cell membrane  (EF04030C)

Substance index (22)： Triphenylphosphine ,  Malonic acid diethyl ,  Acetoacetic acid ethyl ,  Cysteamine ,  4-Chlorophenyl isothiocyanate ,  Cyclohexanecarbaldehyde ,  Sodium ethoxide ,  Ethanol ,  5α-[2-(1H-Imidazole-4-yl)ethyl]tetrahydrofuran-2β-methanamine ,  1-Trityl-4-(chloromethyl)-1H-imidazole ,  (1-Trityl-1H-imidazole-4-ylmethyl)triphenylphosphonium ,  (1H-Imidazole-4-ylmethyl)triphenylphosphonium ,  2-[(4-Imidazolyl)methyl]malonic acid diethyl ester ,  2-(1H-Imidazole-4-ylmethyl)-3-oxobutyric acid ethyl ester ,  3-Oxo-5-phenylvaleric acid ethyl ester ,  3-Oxo-5-phenylhexanoic acid ethyl ester ,  1-(1H-Imidazole-4-yl)-5-phenyl-3-pentanone ,  1-(1H-Imidazole-4-yl)-6-phenyl-3-hexanone ,  1-[2-[(1H-Imidazole-4-yl)methylthio]ethyl]-3-(4-chlorophenyl)thiourea ,  4-[(Z)-2-Cyclohexylvinyl]-1H-imidazole-1-carboxylic acid ethyl ester ,  4-[(E)-2-Cyclohexylvinyl]-1H-imidazole-1-carboxylic acid ethyl ester ,  (2R)-5α-(tert-Butyldiphenylsiloxymethyl)oxolane-2β-carbaldehyde

Terms in the title (4)： 塩 ,  ヒスタミン ,  リガンド ,  研究