Art

J-GLOBAL ID：201002204871213116   Reference number：10A0217111

Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers

Aβモノマーの低濃度におけるAβアミロイド原線維の核形成での界面及び攪拌の重要な役割

Author (9)： MORINAGA Akiyoshi (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...) ,  MORINAGA Akiyoshi (Dep. of Neurology and Neurobiology of Aging, Kanazawa Univ. Graduate School of Medical Sci., Kanazawa 920-8640, JPN) ,  HASEGAWA Kazuhiro (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...) ,  NOMURA Ryo (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...) ,  OOKOSHI Tadakazu (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...) ,  OZAWA Daisaku (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...) ,  GOTO Yuji (Inst. for Protein Res., Osaka Univ., Osaka 565-0871, JPN) ,  YAMADA Masahito (Dep. of Neurology and Neurobiology of Aging, Kanazawa Univ. Graduate School of Medical Sci., Kanazawa 920-8640, JPN) ,  NAIKI Hironobu (Div. of Molecular Pathology, Dep. of Pathological Sciences, Fac. of Medical Sciences, Univ. of Fukui, Fukui 910-1193 ...)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1804  Issue： 4  Page： 986-995  Publication year： Apr. 2010 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *amyloid ,  amyloid beta-protein ,  Alzheimer disease ,  amyloidosis ,  gas-liquid interface ,  polymerization ,  *nucleation ,  monomer ,  microscopy ,  intramolecular interaction ,  concentration dependence ,  peptide
Semi thesaurus term： *amyloid fibril ,  *amyloid fibril formation ,  Amyloidosis ,  monomer ,  fluorescence spectral analysis ,  polymerization ,  amyloid beta-peptide

JST classification (3)： Proteins and peptides in general  (EB03010N) ,  Biological function  (EB03040U) ,  Basic neurology  (GN01020W)

Substance index (1)： Thioflavin T

Terms in the title (7)： モノマー ,  低濃度 ,  アミロイド原線維 ,  核形成 ,  界面 ,  攪拌 ,  役割