Art

J-GLOBAL ID：201002219141602840   Reference number：10A0994654

Design of New Scaffolds for Increased Superbasicity of Bisguanidine Proton Sponges

ビスグアニジンプロトンスポンジの強化した超塩基性のための新しい足場の設計

Author (4)： MARGETIC Davor (Lab. for Physical-Organic Chemistry, Div. of Organic Chemistry and Biochemistry, Ruder Boskovic Inst.) ,  TROSELJ Pavle (Lab. for Physical-Organic Chemistry, Div. of Organic Chemistry and Biochemistry, Ruder Boskovic Inst.) ,  ISHIKAWA Tsutomu (Graduate School of Pharmaceutical Sciences, Chiba Univ.) ,  KUMAMOTO Takuya (Graduate School of Pharmaceutical Sciences, Chiba Univ.)
Material： Bulletin of the Chemical Society of Japan  (Bull Chem Soc Jpn)
Volume： 83  Issue： 9  Page： 1055-1057 (J-STAGE)  Publication year： 2010 
JST Material Number： G0450A  ISSN： 0009-2673  CODEN： BCSJA8  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,  *proton ,  *porous medium ,  *base (alkali) ,  *substrate (biochemistry) ,  proton affinity ,  density functional method ,  molecular design ,  *sponge ,  *super base ,  *scaffold
Semi thesaurus term： *ビスグアニジン類 ,  B3LYP method

JST classification (2)： Acid-base equilibrium  (CB04020D) ,  Aromatic monocyclic ureas,carbamic acids,guanidines  (CF05220O)

Substance index (4)： 1,2-Bis(1,3-dimethylimidazolidine-2-ylideneamino)benzene ,  N,N′-Bis(1,3-dimethylimidazolidine-2-ylidene)-7,12-dihydrobenzo[5,6]cyclohepta[1,2,3-de]naphthalene-7β,12β-diamine ,  N,N′-Bis[bis[[2,3-bis(dimethylamino)-2-cyclopropene-1-ylidene]amino]methylene]-6,7,8,9-tetrahydro-5H-benzocycloheptene-5β,9β-diamine ,  N,N′-Bis(1,3-dimethylimidazolidine-2-ylidene)-2,3,3aβ,4,4aβ,5,6,7,7a,9a-decahydro-8,9-[1,3]butadieno-1H-cyclopenta[f]azulene-7aα,9aα-diamine

Reference (19)：

• 1) T. Ishikawa, Superbases for Organic Synthesis: Guanidines, Amidines, Phosphazenes and Related Organocatalysts, Wiley, Chichester, 2009.
• 2) M. P. Coles, P. J. Aragón-Sáez, S. H. Oakley, P. B. Hitchcock, M. G. Davidson, Z. B. Maksic, R. Vianello, I. Leito, I. Kaljurand, D. C. Apperley, J. Am. Chem. Soc. 2009, 131, 16858.
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• 4) Z. Glasovac, M. Vazdar, D. Margetic, Croat. Chem. Acta 2009, 82, 63.
• 5) H. A. Staab, T. Saupe, Angew. Chem., Int. Ed. Engl. 1988, 27, 865.

Terms in the title (4)： 強化 ,  塩基性 ,  足場 ,  設計