Art

J-GLOBAL ID：201002230280223865   Reference number：10A1755017

Perfluorooctanoic acid (PFOA) but not perfluorooctane sulfonate (PFOS) showed DNA damage in comet assay on Paramecium caudatum

ペルフルオロオクタン酸(PFOA)はParamecium caudatumのコメット分析でDNA損傷を示すが,ペルフルオロオクタンスルホン酸(PFOS)は示さない

Author (9)： KAWAMOTO Kosuke (Dep. of Veterinary Medicine, Fac. of Agriculture, Iwate Univ.) ,  KAWAMOTO Kosuke (Dep. of Applied Veterinary Sci., The Doctoral Course of the United Graduate School of Veterinary Sci., Gifu Univ.) ,  OASHI Takahiro (Dep. of Veterinary Medicine, Fac. of Agriculture, Iwate Univ.) ,  OAMI Kazunori (Graduate School of Life and Environmental Sciences, Univ. of Tsukuba) ,  LIU Wei (Dep. of Environmental Sci. and Technol., Dalian Univ. of Technol.) ,  JIN Yihe (Dep. of Environmental Sci. and Technol., Dalian Univ. of Technol.) ,  SAITO Norimitsu (Res. Inst. for Environmental Sciences and Public Health of Iwate Prefecture) ,  SATO Itaru (Dep. of Veterinary Medicine, Fac. of Agriculture, Iwate Univ.) ,  TSUDA Shuji (Dep. of Veterinary Medicine, Fac. of Agriculture, Iwate Univ.)
Material： Journal of Toxicological Sciences  (日本毒性学会学術年会プログラム・要旨集)
Volume： 35  Issue： 6  Page： 835-841 (J-STAGE)  Publication year： 2010 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *aliphatic fluorine compound ,...
Semi thesaurus term： Triton X-100

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JST classification (2)： Molecular genetics in general  (EC02010J) ,  Aliphatic halogen compounds  (CF03050P)

Substance index (5)： Perfluorooctanoic acid ,  Perfluorooctanesulfonic acid ,  MNNG ,  8-Hydroxyguanosine ,  Glutathione

Reference (36)：

• 3M Company. (2003): Environmental and health assessment of perfluorooctanesulfonate and its salts. US EPA Administrative Record, AR-226-1486.
• Aoyama, K., Iwahori, K. and Miyata, N. (2003): Application of Euglena gracilis cells to comet assay: evaluation of DNA damage and repair. Mutat. Res., 538, 155-162.
• Abdellatif, A., Al-tonsy, A.H., Awad, M.E., Roberfroid, M. and Khan, M.N. (2003-2004): Peroxisomal enzymes and 8-hydroxydeoxyguanosine in rat liver treated with perfluorooctanoic acid. Dis. Markers, 19, 19-25.
• Anderson, D. and Plewa, M.J. (1998): The International Comet Assay Workshop. Mutagenesis, 13, 67-73.
• Bailly, V., Derydt, M. and Verly, W.G. (1989): Delta-elimination in the repair of AP (apurinic/apyrimidinic) sites in DNA. Biochem. J., 261, 707-713.

Terms in the title (8)： ペルフルオロオクタン酸 ,  PFOA ,  Paramecium ,  コメット ,  分析 ,  DNA損傷 ,  ペルフルオロオクタンスルホン酸 ,  PFOS