Art

J-GLOBAL ID：201002271810272143   Reference number：10A0291643

Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice

マウスにおけるRafの表皮特異的発現によって誘導される好中球優位な乾癬様皮膚炎

Author (8)： TARUTANI Masahito (Dep. of Dermatology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  TARUTANI Masahito (Dep. of Dermatology, Kochi Medical School, Kochi Univ., Nankoku, Kochi 783-8505, JPN) ,  IMAI Yasutomo (Dep. of Dermatology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  IMAI Yasutomo (Dep. of Immunology and Medical Zoology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  YASUDA Koubun (Dep. of Immunology and Medical Zoology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  TSUTSUI Hiroko (Dep. of Microbiology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  NAKANISHI Kenji (Dep. of Immunology and Medical Zoology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN) ,  YAMANISHI Kiyofumi (Dep. of Dermatology, Hyogo Coll. of Medicine, Nishinomiya, Hyogo 663-8501, JPN)
Material： Journal of Dermatological Science  (J Dermatol Sci)
Volume： 58  Issue： 1  Page： 28-35  Publication year： Apr. 2010 
JST Material Number： W1280A  ISSN： 0923-1811  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *MAP kinase kinase kinase ,...
Semi thesaurus term： CD4 positive cell ,...

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JST classification (2)： Basic dermatology  (GF01020Y) ,  Cell physiology in general  (EF02010S)

Substance index (1)： 4-Hydroxytamoxifen

Reference (29)：

• CRESPO, P. Ras proteins in the control of the cell cycle and cell differentiation. Cell Mol Life Sci. 2000, 57, 1613-1636
• SHIELDS, JM. Understanding Ras : 'it ain't over 'til it's over'. Trends Cell Biol. 2000, 10, 147-154
• TARUTANI, M. Inducible activation of Ras and Raf in adult epidermis. Cancer Res. 2003, 63, 319-323
• KHAVARI, TA. Ras/Erk MAPK signaling in epidermal homeostasis and neoplasia. Cell Cycle. 2007, 6, 2928-2931
• SCHOLL, FA. Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin. Oncogene. 2009, 28, 1485-1495

Terms in the title (7)： マウス ,  Raf ,  表皮 ,  発現 ,  誘導 ,  好中球 ,  乾癬様皮膚炎