Nakabayashi Jun

ナカバヤシジュン | Nakabayashi Jun

Affiliation and department：

Research field (1)： Biological, health, and medical informatics

Research keywords (5)：ウイルス-ホスト共進化 , 細胞内ウイルス複製動態 , systems biology , mathematical model , intracellular signal transduction

Research theme for competitive and other funds (6)：

2020 - 2023 Understanding of the impact of infection microenvironment in HIV reactivation and cell-to-cell transmission
2019 - 2022 Molecular mechanisms underlying early dendritic cell lineage specification
2018 - 2021 Regulome analysis of transcriptional regulatory network of immune suppressor cell differentiation in tumor micro environment
2018 - 2020 Evaluation of a cell lineage determination model that converts genomic distances into stochasticity
2015 - 2018 Comprehensive analysis of gene expression regulation during mononuclear phagocyte development

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Papers (23)：

Koichi Murakami, Haruka Sasaki, Akira Nishiyama, Daisuke Kurotaki, Wataru Kawase, Tatsuma Ban, Jun Nakabayashi, Satoko Kanzaki, Yoichi Sekita, Hideaki Nakajima, et al. A RUNX-CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes. Nature Immunology. 2021. 22. 3. 301-311
Kyoko Ochiai, Mari Yamaoka, Amrutha Swaminathan, Hiroki Shima, Hitoshi Hiura, Mitsuyo Matsumoto, Daisuke Kurotaki, Jun Nakabayashi, Ryo Funayama, Keiko Nakayama, et al. Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4. Cell reports. 2020. 33. 12. 108517-108517
Caleb AA, Akiyama T, Kimura A, Kimura Y, Takahashi-Jitsuki A, Nakamura H, Makihara H, Masukawa D, Nakabayashi J, Hirano H, et al. Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer's disease. Neurobiology of disease. 2019. 132. 104603-104603
Daisuke Kurotaki, Wataru Kawase, Haruka Sasaki, Jun Nakabayashi, Akira Nishiyama, Herbert C Morse 3rd, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura. Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice. Blood. 2019. 133. 17. 1803-1813
Haruko Nakamura, Aoi Takahashi-Jitsuki, Hiroko Makihara, Tetsuya Asano, Yayoi Kimura, Jun Nakabayashi, Naoya Yamashita, Yuko Kawamoto, Fumio Nakamura, Toshio Ohshima, et al. Proteome and behavioral alterations in phosphorylation-deficient mutant Collapsin Response Mediator Protein2 knock-in mice. Neurochemistry international. 2018. 119. 207-217

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MISC (8)：

Daisuke Kurotaki, Jun Nakabayashi, Akira Nishiyama, Haruka Sasaki, Naofumi Kaneko, Wataru Kawase, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura. Transcription factor IRF8 governs enhancer landscape dynamics during mononuclear phagocyte development. JOURNAL OF IMMUNOLOGY. 2017. 198. 1
Sasaki H, Nishiyama A, Koizumi S, Nakabayashi J, Kaneko N, Yokota A, Hirai H, Tamura T. C/EBPβ mediates the repression of Irf8 expression and dendritic cell development by BCR-ABL. The 78th Annual Meeting of the Japanese Society of Hematology. 2016
D. Kurotaki, J. Nakabayashi, A. Nishiyama, H. Sasaki, N. Kaneko, K. Ozato, Y. Suzuki, T. Tamura. Hierarchical regulation of enhancer establishment and gene expression by transcription factors during mononuclear phagocyte development. EUROPEAN JOURNAL OF IMMUNOLOGY. 2016. 46. 6-6
Daisuke Kurotaki, Jun Nakabayashi, Akira Nishiyama, Haruka Sasaki, Naofumi Kaneko, Shin-ichi Koizumi, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura. Enhancer Landscape Dynamics and the Role of IRF8 in Mononuclear Phagocyte Development. BLOOD. 2015. 126. 23
Daisuke Kurotaki, Jun Nakabayashi, Akira Nishiyama, Haruka Sasaki, Naofumi Kaneko, Shin-ichi Koizumi, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura. ENHANCER LANDSCAPE DYNAMICS DURING MONOCYTE AND DENDRITIC CELL DEVELOPMENT AND THE ROLE OF THE TRANSCRIPTION FACTOR IRF8. EXPERIMENTAL HEMATOLOGY. 2015. 43. 9. S98-S98

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Professional career (2)：

医学博士 (熊本大学)
理学博士 (九州大学)

Work history (2)：

2011/04 - University of Tokyo, Department of mathematical informatics post doctoral fellow
2008/04 - 2011/03 Graduate University for Advanced Studies, Department of Evolutionary Studies of Biosystems post doctoral fellow

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