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J-GLOBAL ID：202102256488411012   Reference number：21A0160887

Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4

クロマチン蛋白質PC4はIKAROSおよびIRF4と協調してB細胞分化を調整する【JST・京大機械翻訳】

Author (22)： Ochiai Kyoko (Department of Biochemistry, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Yamaoka Mari (Department of Biochemistry, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Swaminathan Amrutha (Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India) ,  Shima Hiroki (Department of Biochemistry, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Hiura Hitoshi (Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Matsumoto Mitsuyo (Department of Biochemistry, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Matsumoto Mitsuyo (Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Kurotaki Daisuke (Department of Immunology, Yokohama City University Graduate School of Medicine, Fukuura 3-9, Yokohama 236-0004, Japan) ,  Nakabayashi Jun (Advanced Medical Research Center, Yokohama City University, Fukuura 3-9, Yokohama 236-0004, Japan) ,  Funayama Ryo (Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Funayama Ryo (Division of Cell Proliferation, United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Nakayama Keiko (Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Nakayama Keiko (Division of Cell Proliferation, United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Arima Takahiro (Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Ikawa Tomokatsu (Division of Immunobiology, Tokyo University of Science, Yamazaki 2669, Noda 278-0022, Japan) ,  Tamura Tomohiko (Department of Immunology, Yokohama City University Graduate School of Medicine, Fukuura 3-9, Yokohama 236-0004, Japan) ,  Tamura Tomohiko (Advanced Medical Research Center, Yokohama City University, Fukuura 3-9, Yokohama 236-0004, Japan) ,  Sciammas Roger (Center for Immunology and Infectious Diseases, University of California Davis, Davis, CA 95616, USA) ,  Bouvet Philippe (Universite de Lyon, Ecole Normale Superieure de Lyon, Centre de Recherche en Cancerologie de Lyon, Cancer Cell Plasticity Department, UMR INSERM 1052 CNRS 5286, Centre Leon Berard, Lyon, France) ,  Kundu Tapas K. (Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India) ,  Igarashi Kazuhiko (Department of Biochemistry, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan) ,  Igarashi Kazuhiko (Center for Regulatory Epigenome and Diseases, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Sendai 980-8575, Japan)
Material： Cell Reports
Volume： 33  Issue： 12  Page： Null  Publication year： 2020 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The chromatin protein positive...

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Thesaurus term： interaction ,  *chromatin ,  antitumor drug ,  *Proteins ,  human ,  *differentiation (biology) ,  complex (substance) ,  antibody formation ,  gene expression ,  transcription factor ,  Gene Silencing ,  coactivator ,  controlling element ,  molecular genetic phenomenon
Semi thesaurus term： 悪性腫瘍 ,  治療標的 , 【Automatic Indexing@JST】

Author keywords (9)： PC4 ,  chromatin ,  complex purification ,  IKAROS ,  IRF4 ,  mature B cell ,  plasma cell differentiation ,  cell survival ,  human B cell malignancy

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (6)： クロマチン ,  蛋白質 ,  IRF4 ,  協調 ,  B細胞 ,  分化