Brain-specific Phgdh Deletion Reveals a Pivotal Role for L-Serine Biosynthesis in Controlling the Level of D-Serine, an N-methyl-D-aspartate Receptor Co-agonist, in Adult Brain

YANG Jung Hoon; WADA Akira; YOSHIDA Kazuyuki; YOSHIDA Kazuyuki; MIYOSHI Yurika; SAYANO Tomoko; ESAKI Kayoko; KINOSHITA Masami O.; KINOSHITA Masami O.; TOMONAGA Shozo; AZUMA Norihiro; WATANABE Masahiko; HAMASE Kenji; ZAITSU Kiyoshi; MACHIDA Takeo; MESSING Albee; ITOHARA Shigeyoshi; HIRABAYASHI Yoshio; FURUYA Shigeki; FURUYA Shigeki

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J-GLOBAL ID：201102225875023146 Reference number：11A0288799

Brain-specific Phgdh Deletion Reveals a Pivotal Role for L-Serine Biosynthesis in Controlling the Level of D-Serine, an N-methyl-D-aspartate Receptor Co-agonist, in Adult Brain

脳特異的Phgdhの欠損は成体マウスの脳におけるD-セリン,N-メチル-D-アスパラギン酸受容体共アゴニストの水準の制御においてL-セリンの生合成に中枢的役割を示す

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Volume： 285 Issue： 53 Page： 41380-41390 Publication year： Dec. 31, 2010
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Basic psychiatry , Enzyme in general

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