Art

J-GLOBAL ID：201102246704752740   Reference number：11A1087334

SYNTHETIC STUDY OF CARBOCYCLIC CORE OF CORTISTATIN A, AN ANTI-ANGIOGENIC STEROIDAL ALKALOID FROM MARINE SPONGE

海綿からの抗血管新生ステロイドアルカロイド,コルチスタチンAの炭素環コアの合成研究

Author (4)： KOTOKU Naoyuki (Osaka Univ., Osaka, JPN) ,  SUMII Yuji (Osaka Univ., Osaka, JPN) ,  HAYASHI Takeshi (Osaka Univ., Osaka, JPN) ,  KOBAYASHI Motomasa (Osaka Univ., Osaka, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 83  Issue： 7  Page： 1535-1552  Publication year： Jul. 01, 2011 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *steroid alkaloid ,  Porifera ,  pharmacological action ,  angiogenesis ,  antitumor drug ,  chemical synthesis ,  Heck reaction ,  cyclization reaction ,  angiogenesis inhibitory effect ,  invertebrate
Semi thesaurus term： antiangiogenic effect

JST classification (1)： Steroids  (CF10040O)

Substance index (5)： 4-[2-[8-Methylene-1,4-dioxaspiro[4.5]decane-7-yl]ethyl]-1β,4α-bis(methoxymethoxy)-2,3,3aα,4,7,7a-hexahydro-5-(trifluoromethoxy)-7aβ-methyl-1H-indene- ,  8α,17β-Bis(methoxymethoxy)-3,3-(ethylenedioxy)-9a-homo-5α-estrane-9a(10),9(11)-diene ,  8α,17β-Bis(methoxymethoxy)-3,3-(ethylenedioxy)-9a-homo-5β-estrane-9a(10),9(11)-diene ,  9,10α-Dimethyl-8α,17β-bis(methoxymethoxy)-3,3-(ethylenedioxy)estrane-11-ene ,  Cortistatin A

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Terms in the title (7)： 海綿 ,  血管新生 ,  ステロイドアルカロイド ,  コルチスタチンA ,  炭素環 ,  コア ,  研究