Art

J-GLOBAL ID：201102259765556221   Reference number：11A1864802

Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

マウスにおけるオプチニューリンE50Kの過剰発現は,Rab8相互作用をかく乱し,進行性網膜変性症を誘発する

Author (14)： CHI Zai-Long (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  AKAHORI Masakazu (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  OBAZAWA Minoru (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  MINAMI Masayoshi (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  NODA Toru (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  NAKAYA Naoki (National Inst. Of Health, MD, USA) ,  TOMAREV Stanislav (National Inst. Of Health, MD, USA) ,  KAWASE Kazuhide (Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  YAMAMOTO Tetsuya (Gifu Univ. Graduate School of Medicine, Gifu, JPN) ,  NODA Setsuko (Tokai Univ. School of Health Sci., Kanagawa, JPN) ,  SASAOKA Masaki (Santen Pharmaceutical Co., Ltd, Nara, JPN) ,  SHIMAZAKI Atsushi (Santen Pharmaceutical Co., Ltd, Nara, JPN) ,  TAKADA Yuichiro (National Hospital Organization Tokyo Medical Center, Tokyo, JPN) ,  IWATA Takeshi (National Hospital Organization Tokyo Medical Center, Tokyo, JPN)
Material： Human Molecular Genetics  (Hum Mol Genet)
Volume： 19  Issue： 13  Page： 2606-2615  Publication year： Jul. 01, 2010 
JST Material Number： W0445A  ISSN： 0964-6906  CODEN： HMGEE5  Document type： Article
Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Terms in the title (8)： マウス ,  オプチニューリン ,  過剰発現 ,  Rab8 ,  相互作用 ,  かく乱 ,  網膜変性症 ,  誘発