Rchr
J-GLOBAL ID：201201071327312942
Update date: Nov. 15, 2024
Naito Yuki
ナイトウ ユウキ | Naito Yuki
Affiliation and department：
Job title：
Project Associate Professor
Homepage URL (1)：
https://data.dbcls.jp/~meso/meme/
Research field (2)：
Molecular biology
, Genomics
Research keywords (5)：
Nucleic Acids Therapeutics
, Genome editing
, Life Science Databases
, microRNA
, RNA interference
Research theme for competitive and other funds (9)：
- 2019 - 2022 In vivoゲノム編集を利用した遺伝子治療用製品の安全性評価に関する研究
- 2016 - 2019 ゲノム編集を利用した遺伝子治療用製品の安全性評価に関する研究
- 2014 - 2016 Transcript-oriented search engine for genes and transcripts
- 2014 - 2015 統合遺伝子検索エンジンの開発
- 2009 - 2012 Functional analysis of genes associated with miRNA expression
- 2008 - 2011 Analysis of the microRNA regulatory mechanisms based on the development of human microRNA expression vectors
- 2008 - 2010 RNA干渉による1遺伝子特異的発現抑制システムの構築
- 2007 - 2008 効率が高く副作用の少ない抗ウイルスRNA干渉分子の設計と検証
- 2006 - 2007 オフターゲット効果が低く標的遺伝子に特異的なsiRNA設計法の確立
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Papers (36)：
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Shuya Ikeda, Hiromasa Ono, Tazro Ohta, Hirokazu Chiba, Yuki Naito, Yuki Moriya, Shuichi Kawashima, Yasunori Yamamoto, Shinobu Okamoto, Susumu Goto, et al. TogoID: an exploratory ID converter to bridge biological datasets. Bioinformatics. 2022. 38. 17. 4194-4199
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Tokuyuki Yoshida, Kunihiko Morihiro, Yuki Naito, Atsushi Mikami, Yuuya Kasahara, Takao Inoue, Satoshi Obika. Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides. Nucleic Acids Research. 2022. 50. 13. 7224-7234
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Kazuaki Yamaguchi, Mitsutaka Kadota, Osamu Nishimura, Yuta Ohishi, Yuki Naito, Shigehiro Kuraku. Technical considerations in Hi-C scaffolding and evaluation of chromosome-scale genome assemblies. Molecular ecology. 2021. 30. 5923-5934
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Kazuaki Yamaguchi, Mitsutaka Kadota, Osamu Nishimura, Yuta Ohishi, Yuki Naito, Shigehiro Kuraku. Practical guide for obtaining and validating chromosome-scale genome assemblies with Hi-C scaffolding. Authorea (preprint). 2021
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bonohu, Rutger A. Vos, Toshiaki Katayama, Hiroyuki Mishima, Shin Kawano, Shuichi Kawashima, Jin-Dong Kim, Yuki Moriya, Toshiaki Tokimatsu, Atsuko Yamaguchi, et al. BioHackathon 2015: Semantics of data for life sciences and reproducible research [version 1; peer review: awaiting peer review]. F1000Research. 2020
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MISC (4)：
Patents (14)：
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特異的塩基配列探索方法
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(European Patent) Method of detecting target base sequence of rna interference, method of designing polynucleotide base sequence causing rna interference, method of constructing double-stranded polynucleotide, method of regulating gene expression, base sequence processing apparatus, program for running base sequence
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RNA干渉ポリヌクレオチド混合物の設計装置、RNA干渉ポリヌクレオチド混合物の作製方法、及びRNA干渉ポリヌクレオチド混合物の設計プログラム
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サンプルセット製造方法、遺伝子整列プログラム及びサンプルセット
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(Australian Patent) Method for searching target base sequence of RNA interference, method for designing base sequence of polynucleotide for causing RNA interference, method for producing double-stranded polynucleotide, method for inhibiting gene expression, base sequence processing apparatus, program for running base sequence processing method on computer, recording medium, and base sequence processing system
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Books (13)：
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完全版ゲノム編集実験スタンダード
羊土社 2019 ISBN:9784758122443
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なぜ、いま核酸医薬なのか : 次なる創薬モダリティの本命(実験医学2019年1月号)
羊土社 2019 ISBN:9784758125154
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今日から使える! データベース・ウェブツール 達人になるための実践ガイド100(実験医学増刊)
羊土社 2014 ISBN:4758103437
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ゲノム編集法の新常識!CRISPR/Casが生命科学を加速する(実験医学2014年7月号)
羊土社 2014 ISBN:4758101299
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新遺伝子工学ハンドブック(改訂第5版)
羊土社 2010 ISBN:4758101779
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Works (9)：
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Drug Search (Japanese)
Yuki Naito 2020 - 現在
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CRISPRdirect: web-based software for designing CRISPR-Cas9 guide RNA with reduced off-target sites
Yuki Naito, Kimihiro Hino, Hidemasa Bono, Kumiko Ui-Tei 2014 - 現在
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Probe Search
Yuki Naito 2013 - 現在
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GGGenome: web-based, ultrafast search engines for nucleotide sequence database
Yuki Naito, Hidemasa Bono 2012 - 現在
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GGRNA: Google-like full text search engine for genes and transcripts
Yuki Naito, Hidemasa Bono 2011 - 現在
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Education (2)：
- 2002 - 2007 The University of Tokyo Graduate School of Science Ph.D., Department of Biophysics and Biochemistry
- 1998 - 2002 The University of Tokyo Faculty of Science B.Sc., Department of Biophysics and Biochemistry
Professional career (1)：
- Ph.D. (The University of Tokyo)
Work history (5)：
- 2024/10 - 現在 Institute of Sciecne Tokyo Graduate School of Medical and Dental Sciences Project Associate Professor
- 2023/04 - 現在 Database Center for Life Science (DBCLS) Visiting Associate Professor
- 2023/04 - 2024/09 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Project Associate Professor
- 2011/04 - 2023/03 Database Center for Life Science (DBCLS) Project Assistant Professor
- 2007/04 - 2011/03 Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo Assistant Professor
Committee career (1)：
- 2018/03 - 現在 医薬品医療機器総合機構(PMDA) 専門委員
Association Membership(s) (2)：
Nucleic Acids Therapeutics Society of Japan
, The Molecular Biology Society of Japan
