Art

J-GLOBAL ID：201202251174228825   Reference number：12A0834367

Development and characterization of a novel drug nanocarrier for oral delivery, based on self-assembled β-casein micelles

自己集合したβカゼインミセルに基づく経口送達を意図した新たな薬物ナノ担体の開発および特徴

Author (8)： BACHAR Michal (Dep. of Biotechnology and Food Engineering, Technion - Israel Inst. of Technol., Haifa 32000, ISR) ,  MANDELBAUM Amitai (Dep. of Biotechnology and Food Engineering, Technion - Israel Inst. of Technol., Haifa 32000, ISR) ,  PORTNAYA Irina (Dep. of Biotechnology and Food Engineering, Technion - Israel Inst. of Technol., Haifa 32000, ISR) ,  PERLSTEIN Hadas (Lab. of Membrane and Liposome Res., IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, ISR) ,  EVEN-CHEN Simcha (Lab. of Membrane and Liposome Res., IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, ISR) ,  BARENHOLZ Yechezkel (Lab. of Membrane and Liposome Res., IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem 91120, ISR) ,  DANINO Dganit (Dep. of Biotechnology and Food Engineering, Technion - Israel Inst. of Technol., Haifa 32000, ISR) ,  DANINO Dganit (Russell Berrie Nanotechnology Inst., Technion - Israel Inst. of Technol., Haifa 32000, ISR)
Material： Journal of Controlled Release  (J Control Release)
Volume： 160  Issue： 2  Page： 164-171  Publication year： Jun. 10, 2012 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： self assembly ,...
Semi thesaurus term： non-steroidal anti-inflammatory agent ,...

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JST classification (2)： Pharmaceutics in general  (GY01011J) ,  Polymer chemistry in general  (CG01000B)

Substance index (1)： Celecoxib

Reference (51)：

• B. Ribadeau Dumas, et al., Primary structure of bovine beta casein. Complete sequence, Eur. J. Biochem. 25 (3) (1972) 505-514.
• H.M. Farrell, et al., Secondary structural studies of bovine caseins: temperature dependence of beta-casein structure as analyzed by circular dichroism and FTIR spectroscopy and correlation with micellization, Food Hydrocolloids 15 (4-6) (2001) 341-354.
• P. Tompa, Intrinsically unstructured proteins, Trends Biochem. Sci. 27 (10) (2002) 527-533.
• A.K. Dunker, et al., Intrinsically disordered protein, J. Mol. Graph. Model. 19 (1) (2001) 26-59.
• A.L. Andrews, et al., Conformation and aggregation of bovine beta-casein-A. 1. Molecular aspects of thermal aggregation, Biopolymers 18 (5) (1979) 1105-1121.

Terms in the title (7)： 自己集合 ,  カゼインミセル ,  送達 ,  意図 ,  薬物 ,  ナノ担体 ,  開発