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J-GLOBAL ID：201302233180399339   Reference number：13A1056787

Molecular basis of muscle hypertrophy and atrophy: Potential therapy for muscular dystrophy

筋肥大と筋萎縮の分子基盤:筋ジストロフィーに対する有効な治療

Author (4)： ITO Naoki (National Center of Neurology and Psychiatry, Tokyo, JPN) ,  ITO Naoki (Tokyo Inst. Technol., Kanagawa, JPN) ,  MIYAGOE-SUZUKI Yuko (National Center of Neurology and Psychiatry, Tokyo, JPN) ,  TAKEDA Shin'ichi (National Center of Neurology and Psychiatry, Tokyo, JPN)
Material： Journal of Physical Fitness and Sports Medicine  (J Phys Fit Sports Med)
Volume： 2  Issue： 2  Page： 179-184  Publication year： May. 25, 2013 
JST Material Number： L8465A  ISSN： 2186-8131  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： muscular disease ,...
Semi thesaurus term： Canis lupus ,...

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JST classification (2)： Basic medicine on musculoskeletal system  (GG01020B) ,  Cell physiology in general  (EF02010S)

Reference (63)：

• Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD and Glass DJ. 2004. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 14: 395-403.
• Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ and Yancopoulos GD. 2001. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 3: 1014-1019.
• Nikawa T, Ishidoh K, Hirasaka K, Ishihara I, Ikemoto M, Kano M, Kominami E, Nonaka I, Ogawa T, Adams GR, Baldwin KM, Yasui N, Kishi K and Takeda S. 2004. Skeletal muscle gene expression in space-flown rats. FASEB J 18:522-524.
• Llovera M, Garcia-Martinez C, Agell N, Marzabal M, Lopez- Soriano FJ and Argiles JM. 1994. Ubiquitin gene expression is increased in skeletal muscle of tumour-bearing rats. FEBS Lett 338: 311-318.
• Voisin L, Breuille D, Combaret L, Pouyet C, Taillandier D, Aurousseau E, Obled C and Attaix D. 1996. Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca²⁺-activated, and ubiquitin-proteasome proteolytic pathways. J Clin Invest 97: 1610-1617.

Terms in the title (6)： 筋肥大 ,  筋萎縮 ,  分子 ,  基盤 ,  筋ジストロフィー ,  治療