Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl] isothioureas: High affinity and human/rat species-selective histamine H <sub>3</sub> receptor antagonists

HARUSAWA Shinya; MAGATA Takuji; YONEYAMA Hiroki; ARAKI Lisa; USAMI Yoshihide; SAWADA Koichi; HATANO Kouta; YAMAMOTO Kouichi; YAMATODANI Atsushi; YAMAMOTO Daisuke

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J-GLOBAL ID：201302289647608200 Reference number：13A1896370

Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl] isothioureas: High affinity and human/rat species-selective histamine H ₃ receptor antagonists

N-アルキル-S-[3-(ピペリジン-1-イル)プロピル]イソチオウレアの合成および評価:高親和性およびヒト/ラット種選択性ヒスタミンH₃受容体アンタゴニスト

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Volume： 23 Issue： 23 Page： 6415-6420 Publication year： 2013
JST Material Number： W0248A ISSN： 0960-894X Document type： Article
Country of issue： Netherlands (NLD) Language： ENGLISH (EN)

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Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl] isothioureas: High affinity and human/rat species-selective histamine H 3 receptor antagonists

Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl] isothioureas: High affinity and human/rat species-selective histamine H ₃ receptor antagonists