Rchr
J-GLOBAL ID：201401033119657400   Update date: Aug. 23, 2024

Kinoh Hiromi

キノウ ヒロミ | Kinoh Hiromi
Affiliation and department：
The University of Tokyo

About The University of Tokyo


Other affiliations (1)：
Homepage URL  (1)： http://kaken.nii.ac.jp/d/r/60532728.ja.html
Research field  (2)： Experimental pathology ,  Neurosurgery
Research keywords  (6)： AAVベクター ,  遺伝子治療 ,  脳神経疾患 ,  神経疾患 ,  ウイルス ,  遺伝子
Research theme for competitive and other funds  (6)：
  • 2022 - 2025 経口減感作による組換えAAVの発現効率の改善-筋ジストロフィー治療を目指して
  • 2022 - 2025 デュシェンヌ型筋ジストロフィーの遺伝子治療を目指した免疫応答回避性薬剤の開発
  • 2016 - 2019 IMPROVED GENE TRANSDUCTION WITH RECOMBINANT AAV FOLLOWING IMMUNE TOLERANCE.
  • 2014 - 2017 Development of rAAV-mediated brain transduction with transient ultrasound-mediated modulation of the blood-brain interface in adult common marmoset toward modeling epilepsy
  • 2014 - 2017 Investigation of immune tolerance induction method for gene therapy of muscular dystrophy
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Papers (25)：
  • Rimi Miyaoka, Yuji Tsunekawa, Yae Kurosawa, Takako Sasaki, Azusa Onodera, Kenji Sakamoto, Yuko Kakiuchi, Mikako Wada, Yuko Nitahara-Kasahara, Hiromi Hayashita-Kinoh, et al. Development of a novel purification method for AAV vectors using tangential flow filtration. Biotechnology and bioengineering. 2023
  • Mikako Wada, Naoya Uchida, Guillermo Posadas-Herrera, Hiromi Hayashita-Kinoh, Yuji Tsunekawa, Yukihiko Hirai, Takashi Okada. Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor. Gene therapy. 2023
  • Hiromi Hayashita-Kinoh, Posadas-Herrera Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Hironori Okada, Tomoko Chiyo, Shin'ichi Takeda, Takashi Okada. Improved transduction of canine X-linked muscular dystrophy with rAAV9-microdystrophin via multipotent MSC pretreatment. Molecular therapy. Methods & clinical development. 2021. 20. 133-141
  • Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Yuki Oda, Hiromi Hayashita-Kinoh, Shin'ichi Takeda, Takashi Okada. Enhanced cell survival and therapeutic benefits of IL-10-expressing multipotent mesenchymal stromal cells for muscular dystrophy. Stem cell research & therapy. 2021. 12. 1. 105-105
  • Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Posadas Herrera Guillermo, Hiromi Hayashita-Kinoh, Yasunobu Maruoka, Aki Nakamura-Takahasi, Koichi Kimura, Shin'ichi Takeda, Takashi Okada. Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy. Stem cell research & therapy. 2021. 12. 1. 78-78
ｍore...
MISC (61)：
  • 喜納(早下)裕美, 笠原優子, 岡田尚巳. Gene and cell therapy for Duchenne muscular dystrophy. 金沢大学十全医学会雑誌. 2024. 133. 1
  • 喜納(早下)裕美, 岡田尚巳. 遺伝子治療 6.AAVベクターを用いた遺伝子治療 脊髄性筋萎縮症・筋ジストロフィー症. 日本医師会雑誌. 2023. 152
  • 宮川世志幸, 丸山基世, 丸山基世, 坂井敦, 佐藤優里子, 黒田誠司, 喜納裕美, 山本基子, 橋詰令太郎, 鈴木秀典, et al. Long-term efficacy and safety of non-toxic herpesvirus vectors. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • 喜納(早下)裕美, 岡田尚巳. 筋ジストロフィーに対する遺伝子細胞治療. MD Frontier. 2023. 3. 1
  • Hiromi Hayashita-Kinoh, Posadas Herrera-Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Shin'ichi Takeda, Takashi Okada. Development of Administration Protocols for Reduction of the Necessary Dose of rAAV for Treatment. MOLECULAR THERAPY. 2022. 30. 4. 494-494
ｍore...
Patents (3)：
Professional career (1)：
  • 博士(医学) (東京大学)
Work history (5)：
  • 2020/10 - 現在 The University of Tokyo The Institute of Medical Science
  • 2008/09 - 現在 National Center of Neurology and Psychiatry
  • 2014/09 - 2020/09 Nippon Medical School
  • 2007/03 - 2008/08 Hiroshima University
  • 2002/04 - 2007/02 Juntendo University
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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