Art

J-GLOBAL ID：201402288981649007   Reference number：14A0813165

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

エピジェネティック調節因子Uhrf1は,大腸の制御性T細胞の増殖と成熟を促進する

Author (37)： OBATA Yuuki (Univ. Tokyo, Tokyo, JPN) ,  OBATA Yuuki (Chiba Univ., Chiba, JPN) ,  OBATA Yuuki (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  OBATA Yuuki (Yokohama City Univ., Kanagawa, JPN) ,  FURUSAWA Yukihiro (Univ. Tokyo, Tokyo, JPN) ,  FURUSAWA Yukihiro (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  FURUSAWA Yukihiro (Keio Univ., Tokyo, JPN) ,  ENDO Takaho A (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  SHARIF Jafar (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  TAKAHASHI Daisuke (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  ATARASHI Koji (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  ATARASHI Koji (JST-PRESTO, Saitama, JPN) ,  NAKAYAMA Manabu (Kazusa DNA Res. Inst., Chiba, JPN) ,  ONAWA Satoshi (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  FUJIMURA Yumiko (Univ. Tokyo, Tokyo, JPN) ,  FUJIMURA Yumiko (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  TAKAHASHI Masumi (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  IKAWA Tomokatsu (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  IKAWA Tomokatsu (JST-PRESTO, Saitama, JPN) ,  OTSUBO Takeshi (National Center for Global Health and Medicine, Chiba, JPN) ,  KAWAMURA Yuki I (National Center for Global Health and Medicine, Chiba, JPN) ,  DOHI Taeko (National Center for Global Health and Medicine, Chiba, JPN) ,  TAJIMA Shoji (Osaka Univ., Osaka, JPN) ,  MASUMOTO Hiroshi (Kazusa DNA Res. Inst., Chiba, JPN) ,  OHARA Osamu (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  HONDA Kenya (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  HONDA Kenya (JST-CREST, Saitama, JPN) ,  HORI Shohei (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  OHNO Hiroshi (Chiba Univ., Chiba, JPN) ,  OHNO Hiroshi (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  OHNO Hiroshi (Yokohama City Univ., Kanagawa, JPN) ,  KOSEKI Haruhiko (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  HASE Koji (Univ. Tokyo, Tokyo, JPN) ,  HASE Koji (RIKEN Center for Integrative Medical Sci., Kanagawa, JPN) ,  HASE Koji (Yokohama City Univ., Kanagawa, JPN) ,  HASE Koji (JST-PRESTO, Saitama, JPN) ,  HASE Koji (Keio Univ., Tokyo, JPN)
Material： Nature Immunology  (Nat Immunol)
Volume： 15  Issue： 6  Page： 571-579  Publication year： Jun. 2014 
JST Material Number： W1330A  ISSN： 1529-2908  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *large intestine ,  *mucosal immunity ,  DNA binding protein ,  *tumor suppressor protein ,  Methylation ,  knockout mouse ,  Inflammation ,  Microbiome ,  Mus musculus ,  germ-free animal ,  *regulatory T cell ,  T cell ,  *epigenetics regulation ,  *UHRF1 ,  *Cyclin-Dependent Kinase Inhibitor p21 ,  *DNA Methylation ,  Conditional knockout mice ,  germ-free mouse ,  Gene Expression Regulation ,  intestinal flora ,  laboratory animal ,  Myomorpha ,  Heredity
Semi thesaurus term： genetic regulation ,  T lymphocyte ,  intestinal flora

JST classification (3)： Biophylaxis and immune systems in general  (ED01010F) ,  Immunological reaction in general  (ED03010T) ,  Gene expression  (EC02040Q)

Terms in the title (8)： エピジェネティック ,  調節因子 ,  UHRF1 ,  大腸 ,  制御性T細胞 ,  増殖 ,  成熟 ,  促進