Research keywords (2):
Protein degradation
, Ubiquitin
Research theme for competitive and other funds (13):
2021 - 2024 細菌感染に対して有効な宿主免疫賦活化薬剤の創出
2020 - 2024 病原因子の分解を誘導する分子標的型新規抗菌剤の開発基盤の構築
2020 - 2024 病原細菌エフェクターによるNF-κB経路を標的とした感染機構の解析
2020 - 2023 もやもや病や脳梗塞の遺伝性リスク因子の機能解析
2017 - 2020 Bacteria Hijack host ubiquitin system
2015 - 2018 Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infection
2015 - 2017 バクテリアが持つユビキチン修飾システム
2013 - 2015 バクテリアが利用するユビキチンシステム
2013 - 2015 細菌病原因子と宿主標的蛋白質の相互作用基盤
2012 - 2015 Structural analyses of bacterial effectors and their mechanisms of infection
2011 - 2014 Development of new therapeutic tools against pathogenic bacteria
2008 - 2009 Analysis of host cell cycle arrest mechanism by EPEC infection
2005 - 2006 病原性大腸菌の粘膜上皮感染における細菌エフェクタータンパク質の役割解明
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Papers (35):
Keito Hiragi, Akira Nishide, Kenji Takagi, Kazuhiro Iwai, Minsoo Kim, Tsunehiro Mizushima. Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. The Journal of Biochemistry. 2023
Akira Nishide, Kenji Takagi, Minsoo Kim, Tsunehiro Mizushima. Active site structure of the Shigella flexneri effector OspI. 2022
Minsoo Kim, Shigeki Nishimori, Yoshikazu Tanaka, Keiii Tanaka, Tomoki Chiba. The role and mechanism of p57(kip2) degradation during TGF-beta 1 signaling. CELL STRUCTURE AND FUNCTION. 2005. 30. 99-99