Art

J-GLOBAL ID：201502228591071394   Reference number：15A0409316

Oscillation of cAMP and Ca²⁺ in cardiac myocytes: a systems biology approach

心筋細胞におけるcAMPおよびCa²⁺のオシレーション:システム生物学的アプローチ

Author (21)： KAMIDE Takehisa (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  OKUMURA Satoshi (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  OKUMURA Satoshi (Tsurumi Univ. School of Dental Medicine, Yokohama, JPN) ,  GHOSH Samik (Systems Biology Inst., Tokyo, JPN) ,  SHINODA Yoko (Tsurumi Univ. School of Dental Medicine, Yokohama, JPN) ,  MOTOTANI Yasumasa (Tsurumi Univ. School of Dental Medicine, Yokohama, JPN) ,  OHNUKI Yoshiki (Tsurumi Univ. School of Dental Medicine, Yokohama, JPN) ,  JIN Huiling (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  CAI Wenqian (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SUITA Kenji (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SATO Itaru (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  UMEMURA Masanari (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  FUJITA Takayuki (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  YOKOYAMA Utako (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SATO Motohiko (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SATO Motohiko (Aichi Medical Univ., Aichi, JPN) ,  FURUTANI Kazuharu (Osaka Univ., Osaka, JPN) ,  KITANO Hiroaki (Systems Biology Inst., Tokyo, JPN) ,  KITANO Hiroaki (Okinawa Inst. Sci. and Technol. Graduate School, Okinawa, JPN) ,  KITANO Hiroaki (Riken, Yokohama, JPN) ,  ISHIKAWA Yoshihiro (Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN)
Material： Journal of Physiological Sciences (Web)
Volume： 65  Issue： 2  Page： 195-200  Publication year： Mar. 2015 
JST Material Number： U1505A  ISSN： 1880-6546  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *cardiac myocyte ,...
Semi thesaurus term： Calcium Signaling ,...

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JST classification (3)： Muscloskeletal system,skin models  (EL02040R) ,  Heart  (EJ04020D) ,  Cell physiology in general  (EF02010S)

Substance index (1)： cAMP

Reference (35)：

• Okumura S, Suzuki S, Ishikawa Y (2009) New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: effects of targeted disruption of the type 5 adenylyl cyclase gene. J Pharmacol Sci 109:354-359
• Okumura S, Kawabe J, Yatani A, Takagi G, Lee MC, Hong C, Liu J, Takagi I, Sadoshima J, Vatner DE, Vatner SF, Ishikawa Y (2003) Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res 93:364-371
• Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, Ishikawa Y (2014) EPAC1-dependent phospholamban phosphorylation mediates the cardiac response to stresses. J Clin Invest 124:2785-2801
• Ohnuki Y, Nishimura S, Sugiura S, Saeki Y (2008) Phosphorylation status of regulatory proteins and functional characteristics in myocardium of dilated cardiomyopathy of Syrian hamsters. J Physiol Sci 58:15-20
• Bers DM (2002) Calcium and cardiac rhythms: physiological and pathophysiological. Circ Res 90:14-17

Terms in the title (4)： 心筋細胞 ,  cAMP ,  オシレーション ,  システム生物学