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J-GLOBAL ID：201502256839798800   Reference number：15A0133837

フィブリノゲンBβ鎖448残基の遺伝子多型(Arg/Lys)の頻度と血中濃度・凝固機能の相違

Author (4)： TERASAWA FUMIKO (信州大 医 保健学科) ,  IKEDA MINAMI ,  ARAI SHIMPEI ,  OKUMURA NOBUO (信州大 医 保健学科)
Material： 臨床病理  (日本臨床検査医学会誌)
Volume： 62  Issue： 12  Page： 1185-1190  Publication year： Dec. 25, 2014 
JST Material Number： Z0687A  ISSN： 0047-1860  CODEN： RBYOAI  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *fibrinogen ,...
Semi thesaurus term： RFLP ,...

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JST classification (3)： Blood tests(=hematologic tests)  (GC02050D) ,  Biological function  (EB03040U) ,  Molecular genetics in general  (EC02010J)

Reference (14)：

• Doolittle RF. Fibrinogen and fibrin. Sci Amer 1981; 245: 92-101.
• Baumann RE, Henschen AH. Human fibrinogen polymorphic site analysis by restriction endonuclease digestion and allele-specific polymerase chain reaction amplification: identification of polymorphisms at positions Aα 312 and Bβ 448. Blood 1993; 82: 2117-24.
• Schmelzer CH, Ebert RF, Bell WR. A polymorphism at Bβ 448 of fibrinogen identified during structural studies of fibrinogen Baltimore II. Thromb Res 1988; 52: 173-7.
• Behague I, Porier O, Nicaud V, et al. Beta fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction. Circulation 1996; 93: 440-9.
• Carter AM, Catto AJ, Bamford JM, et al. Gender-specific associations of the fibrinogen Bβ 448 polymorphism, fibrinogen levels and acute cerebrovascular disease. Arterioscler Thromb Vasc Biol 1997; 17: 589-94.

Terms in the title (8)： フィブリノゲン ,  残基 ,  遺伝子多型 ,  Lys ,  頻度 ,  血中濃度 ,  凝固 ,  相違