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J-GLOBAL ID：201602214206104182   Reference number：16A1349341

The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918

ダイゼインからのS-エクオールの産生はEggerthella属YY7918における3つの遺伝子クラスタと関連する

Author (5)： KAWADA Yuika (The United Graduate School of Agricultural Science, Gifu University, Gifu 501-1193, Japan) ,  YOKOYAMA Shinichiro (Department of Food Technology, Industrial Technology Center, Gifu Prefectural Government, Gifu 501-6064, Japan) ,  YANASE Emiko (Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan) ,  NIWA Toshio (Faculty of Health and Nutrition, Shubun University, Aichi 491-0938, Japan) ,  SUZUKI Tohru (Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan)
Material： Bioscience of Microbiota, Food and Health (Web)  (Biosci Microbiota Food Health (Web))
Volume： 35  Issue： 3  Page： 113-121(J-STAGE)  Publication year： 2016 
JST Material Number： U0398A  ISSN： 2186-3342  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： enteric microbe ,...
Semi thesaurus term： Lactococcus ,...

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Author keywords (6)： equol ,  daidzein ,  isoflavone ,  gut-microflora ,  oxidoreductase ,  dismutase

JST classification (2)： Structure and chemistry of genes  (EC02020U) ,  Gene manipulation  (EC02050B)

Substance index (4)： Daidzein ,  Equol ,  Dihydrodaidzein ,  NADPH

Reference (35)：

• 1. Bowey E, Adlercreutz H, Rowland I. 2003. Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats. Food Chem Toxicol 41: 631-636.
• 2. Joannou GE, Kelly GE, Reeder AY, Waring M, Nelson C. 1995. A urinary profile study of dietary phytoestrogens. The identification and mode of metabolism of new isoflavonoids. J Steroid Biochem Mol Biol 54: 167-184.
• 3. Hur H, Rafii F. 2000. Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum. FEMS Microbiol Lett 192: 21-25.
• 4. Willard ST, Frawley LS. 1998. Phytoestrogens have agonistic and combinatorial effects on estrogen-responsive gene expression in MCF-7 human breast cancer cells. Endocrine 8: 117-121.
• 5. Tousen Y, Ezaki J, Fujii Y, Ueno T, Nishimuta M, Ishimi Y. 2011. Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial. Menopause 18: 563-574.

Terms in the title (3)： ダイゼイン ,  エクオール ,  遺伝子クラスタ