Art

J-GLOBAL ID：201702213154787203   Reference number：17A1688901

Antiangiogenic agent sunitinib induces epithelial to mesenchymal transition and accelerates motility of colorectal cancer cells

抗血管新生薬,スニチニブは上皮間葉移行を誘導し,結腸直腸癌細胞の動きを加速する

Author (8)： Tomida Chisato (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School) ,  Yamagishi Naoko (Department of Anatomy and Cell Biology, School of Medicine, Wakayama Medical University) ,  Nagano Hikaru (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School) ,  Uchida Takayuki (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School) ,  Ohno Ayako (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School) ,  Hirasaka Katsuya (Graduate school of Fisheries Science and Environmental Studies, Nagasaki University) ,  Nikawa Takeshi (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School) ,  Teshima-Kondo Shigetada (Department of Physiological Nutrition, Institute of Medical Nutrition, University of Tokushima Graduate School)
Material： Journal of Medical Investigation (Web)  (J Med Invest (Web))
Volume： 64  Issue： 3.4  Page： 250-254(J-STAGE)  Publication year： 2017 
JST Material Number： U0711A  ISSN： 1349-6867  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： angiogenesis inhibitor ,...
Semi thesaurus term： cell physiology ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A1688901&from=J-GLOBAL&jstjournalNo=U0711A") }}

Author keywords (3)： VEGF receptor tyrosine kinase inhibitor ,  sunitinib ,  evasive adaptation

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Sunitinib

Reference (28)：

• 1. Bergers G, Hanahan D: Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8: 592-603, 2008
• 2. Ellis LM, Reardon DA: Is there really a yin and yang to VEGF-targeted therapies? Lancet Oncol 11: 809-811, 2010
• 3. Jayson GC, Kerbel R, Ellis LM, Harris AL: Antiangiogenic therapy in oncology: current status and future directions. Lancet 388: 518-529, 2016
• 4. Meadows KL, Hurwitz HI: Anti-VEGF therapies in the clinic. Cold Spring Harb Perspect Med 2: a006577, 2012
• 5. Bottsford-Miller JN, Coleman RL, Sood AK: Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies. J Clin Oncol 30: 4026-4034, 2012

Terms in the title (8)： 抗血管新生薬 ,  スニチニブ ,  上皮間葉移行 ,  誘導 ,  結腸直腸 ,  癌細胞 ,  動き ,  加速