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J-GLOBAL ID：201702215880063421   Reference number：17A1812384

Biological Activities of Novel Derivatives of Differentiation-Inducing Factor 3 from Dictyostelium discoideum

Dictyostelium discoideumからの分化誘導因子3の新規誘導体の生物活性

Author (7)： Takahashi Katsunori (Department of Medical Technology, Faculty of Health Science, Gunma Paz College) ,  Kikuchi Haruhisa (Laboratory of Natural Product Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University) ,  Nguyen Van Hai (Laboratory of Natural Product Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University) ,  Oshima Yoshiteru (Laboratory of Natural Product Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University) ,  Ishigaki Hirotaka (Department of Medical Technology, Faculty of Health Science, Gunma Paz College) ,  Nakajima-Shimada Junko (Department of Molecular and Cellular Parasitology, Graduate School of Health Sciences, Gunma University) ,  Kubohara Yuzuru (Laboratory of Health and Life Science, Graduate School of Heath and Sports Science, Juntendo University)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 40  Issue： 11  Page： 1941-1947(J-STAGE)  Publication year： 2017 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *differentiation inducing factor ,...
Semi thesaurus term： *Dictyostelium discoideum ,...

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Author keywords (10)： anti-tumor agent ,  Dictyostelium discoideum ,  interleukin-2 ,  Jurkat cell ,  Trypanosoma cruzi ,  anti-tumor agent ,  Dictyostelium discoideum ,  interleukin-2 ,  Jurkat cell ,  Trypanosoma cruzi

JST classification (1)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y)

Substance index (1)： DIF-3

Reference (33)：

• 1) Morris HR, Taylor GW, Masento MS, Jermyn KA, Kay RR. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. Nature, 328, 811-814 (1987).
• 2) Morris HR, Masento MS, Taylor GW, Jermyn KA, Kay RR. Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum. Biochem. J., 249, 903-906 (1988).
• 3) Kay RR, Berks M, Traynor D. Morphogen hunting in Dictyostelium discoideum. Development (Suppl.), l81-l190 (1989).
• 4) Kay RR, Flatman P, Thompson CRL. DIF signalling and cell fate. Semin. Cell Dev. Biol., 10, 577-585 (1999).
• 5) Dictyostelium discoideum (dictybase). ‹http://dictybase.org/›

Terms in the title (4)： Dictyostelium ,  分化誘導因子 ,  誘導体 ,  生物活性