Art

J-GLOBAL ID：201702219991016830   Reference number：17A0359950

A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor

新しい予後因子TRIM44は,精巣胚細胞腫瘍で細胞増殖と移動を促進し,アポトーシスを阻害する

Author (18)： Yamada Yuta (Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Yamada Yuta (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Takayama Ken-ichi (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Takayama Ken-ichi (Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan) ,  Fujimura Tetsuya (Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Ashikari Daisaku (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Ashikari Daisaku (Urology, Nihon University School of Medicine, Itabashi-ku, Japan) ,  Obinata Daisuke (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Obinata Daisuke (Urology, Nihon University School of Medicine, Itabashi-ku, Japan) ,  Takahashi Satoru (Urology, Nihon University School of Medicine, Itabashi-ku, Japan) ,  Ikeda Kazuhiro (Division of Gene Regulation and Signal Transduction, Research Center of Genomic Medicine, Saitama Medical University, Saitama, Japan) ,  Kakutani Shigenori (Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Urano Tomohiko (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Fukuhara Hiroshi (Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Homma Yukio (Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Inoue Satoshi (Department of Geriatric Medicine and Anti-Aging Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Inoue Satoshi (Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan) ,  Inoue Satoshi (Division of Gene Regulation and Signal Transduction, Research Center of Genomic Medicine, Saitama Medical University, Saitama, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 1  Page： 32-41  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *testicular neoplasm ,...
Semi thesaurus term： *cell physiology ,...

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Author keywords (5)： Apoptosis ,  immunohistochemistry ,  microarray ,  testicular germ cell tumor ,  TRIM family

JST classification (4)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Urogenital tumors(=neoplasms)  (GM04000S) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (50)：

• Albers P, Albrecht W, Algaba F et al. European Association of Urology. Guidelines on testicular cancer. [Cited 13 June 2015.] Available from URL: http://uroweb.org/guideline/testicular-cancer.
• Hatakeyama S. TRIM proteins and cancer. Nat Rev 2011; 11: 792-804.
• Ikeda K, Inoue S. TRIM proteins as RING finger E3 ubiquitin ligases. Adv Exp Med Biol 2012; 770: 27-37.
• Liu C, Huang X, Hou S, Hu B, Li H. Silencing of tripartite motif (TRIM) 29 inhibits proliferation and invasion and increases chemosensitivity to cisplatin in human squamous cancer NCI-H520 cells. Thorac Cancer 2015; 6(1): 31-7.
• Wang Y, He D, Yang L et al. TRIM26 functions as a novel tumor suppressor of hepatocellular carcinoma and its down regulation contributes to worse prognosis. Biochem Biophys Res Commun 2015; 463: 458-65.

Terms in the title (6)： 予後因子 ,  精巣胚細胞腫瘍 ,  細胞増殖 ,  促進 ,  アポトーシス ,  阻害