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J-GLOBAL ID：201702237296835402   Reference number：17A1825887

A multispecific monoclonal antibody G2 recognizes at least three completely different epitope sequences with high affinity

多特異的モノクローナル抗体G2は高親和性をもつ少なくとも3の完全に異なるエピトープ配列を認識する【Powered by NICT】

Author (8)： Mahmud Md. Nuruddin (The United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan) ,  Oda Masayuki (Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Shimogamo, Sakyo-ku, Kyoto, 606-8522, Japan) ,  Usui Daiki (Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Shimogamo, Sakyo-ku, Kyoto, 606-8522, Japan) ,  Inoshima Yasuo (The United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan) ,  Inoshima Yasuo (Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, Gifu, 501-1193, Japan) ,  Ishiguro Naotaka (The United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan) ,  Ishiguro Naotaka (Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, Gifu, 501-1193, Japan) ,  Kamatari Yuji O. (Life Science Research Center, Gifu University, Gifu, 501-1193, Japan)
Material： Protein Science
Volume： 26  Issue： 11  Page： 2162-2169  Publication year： 2017 
JST Material Number： W2730A  ISSN： 0961-8368  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： A monoclonal antibody (mAb) G2...

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Thesaurus term： antigen ,  *antibody ,  *monoclonal antibody ,  *affinity ,  interaction ,  prion protein ,  Proteins ,  binding site ,  *epitope ,  steric conformation ,  surface plasmon resonance sensor ,  binding affinity ,  Sequence Homology, Amino Acid

Author keywords (4)： multispecific antibody ,  epitope mapping ,  antigen-recognition mechanism ,  surface plasmon resonance

JST classification (3)： Bioassay  (EA03060N) ,  Proteins and peptides in general  (EB03010N) ,  Biochemistry of antigens,antibodies,complements  (ED04020L)

Terms in the title (3)： モノクローナル抗体 ,  親和性 ,  エピトープ