Art

J-GLOBAL ID：201702248255233707   Reference number：17A1004751

Inhibition of β-Secretase Activity by Monoterpenes, Sesquiterpenes, and C₁₃ Norisoprenoids

モノテルペン,セスキテルペンとC₁₃ノルイソプレノイドによるβ-セクレターゼ活性の阻害

Author (5)： Marumoto Shinsuke (Joint Research Center, Kindai University (Former name: Kinki University)) ,  Okuno Yoshiharu (Department of Materials Science, Wakayama National College of Technology) ,  Miyazawa Mitsuo (Graduate School of Materials Science, Nara Institute of Science and Technology) ,  Miyazawa Mitsuo (Graduate School of Science, Osaka City University) ,  Miyazawa Mitsuo (Department of Applied Chemistry, Kindai University (Former name: Kinki University))
Material： Journal of Oleo Science  (J Oleo Sci)
Volume： 66  Issue： 8  Page： 851-855(J-STAGE)  Publication year： 2017 
JST Material Number： G0238A  ISSN： 1345-8957  CODEN： JOSOAP  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Abstract/Point： Inhibition of β-secretase (BAC...

Thesaurus term： monoterpene ,...
Semi thesaurus term： *beta-secretase ,...

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Author keywords (5)： monoterpene ,  sesquiterpene ,  terpenoids ,  C₁₃ norisoprenoid ,  β-Secretase (BACE1) inhibitory activity

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (5)： (+)-Camphor ,  (+)-Fenchone ,  (-)-Camphor ,  (-)-Fenchone ,  Geranyl acetone

Reference (15)：

• 1) Gershenzon, J.; Dudareva, N. The function of terpene natural products in the natural world. Nat. Chem. Biol. 3, 408-414 (2007).
• 2) De Carvalho, C.C.C.R.; Da Fonseca, M.M.R. Biotransformation of terpenes. Biotechnol. Adv. 24, 134-142 (2006).
• 3) Teisseire, P.J. Chemistry of Fragrant Substances (Translated by Cadby, P.A). VCH Publishers, New York (1994).
• 4) Trudgill, P.W. Terpenoid metabolism by Pseudomonas. in The Bacteria. A Treatise on Structure and Function (Gunsalus, I.C. (cons. ed.); Sokatch, J.R.; Ornston, L.N. (ed.-in-chief)). Academic Press Inc., San Diego (1986).
• 5) Sandmann, G. Carotenoid biosynthesis and biotechnological application. Arch. Biochem. Biophys. 385, 4-12 (2001).

Terms in the title (6)： モノテルペン ,  セスキテルペン ,  ノルイソプレノイド ,  β-セクレターゼ ,  活性 ,  阻害