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J-GLOBAL ID：201702252183663660   Reference number：17A1064912

Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells

羊水細胞由来人工多能性幹細胞を用いた3次元皮膚を用いた脊髄髄膜瘤の胎児治療モデル【Powered by NICT】

Author (16)： Kajiwara Kazuhiro (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Kajiwara Kazuhiro (Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo 105-8471, Japan) ,  Tanemoto Tomohiro (Department of Medical Science, Chiba University Graduate School of Medicine, Chiba 260-0856, Japan) ,  Wada Seiji (Maternal-Fetal, Neonatal and Reproductive Medicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan) ,  Karibe Jurii (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Ihara Norimasa (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Ikemoto Yu (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Kawasaki Tomoyuki (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Oishi Yoshie (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Samura Osamu (Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo 105-8471, Japan) ,  Okamura Kohji (Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan) ,  Takada Shuji (Systems BioMedicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan) ,  Akutsu Hidenori (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan) ,  Sago Haruhiko (Maternal-Fetal, Neonatal and Reproductive Medicine, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan) ,  Okamoto Aikou (Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo 105-8471, Japan) ,  Umezawa Akihiro (Department of Reproductive Biology, Center for Regenerative Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan)
Material： Stem Cell Reports
Volume： 8  Issue： 6  Page： 1701-1713  Publication year： 2017 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Myelomeningocele (MMC) is a co...

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Thesaurus term： collagen ,  keratinocyte ,  *pluripotent stem cell ,  *amniotic fluid ,  pregnancy ,  human(primates) ,  Down syndrome ,  artificial skin ,  *induced pluripotent stem cell ,  fibroblast ,  hereditary disease ,  EGF ,  *three dimension
Semi thesaurus term： 出生 ,  *髄膜脊髄瘤 , 【Automatic Indexing@JST】

Author keywords (8)： induced pluripotent stem cells ,  myelomeningocele ,  fetal therapy ,  keratinocytes ,  rock inhibitor ,  epidermal growth factor ,  amniotic fluid ,  polyhydramnion

JST classification (5)： Gynecologic and obstetrical diseases  (GS03000D) ,  Cell physiology in general  (EF02010S) ,  Congenital diseases,deformities in general.  (GD03010V) ,  Basic medicine on cardiovascular system  (GJ01020K) ,  Cell and tissue culture methods  (EA03040R)

Terms in the title (8)： 羊水 ,  細胞 ,  人工多能性幹細胞 ,  3次元 ,  皮膚 ,  脊髄髄膜瘤 ,  胎児治療 ,  モデル