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J-GLOBAL ID：201702253639264316   Reference number：17A1240921

Highly recurrent H3F3A mutations with additional epigenetic regulator alterations in giant cell tumor of bone

骨巨細胞腫における付加的なエピジェネティック調節因子変化と高再発H3F3A変異【Powered by NICT】

Author (16)： Ogura Koichi (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Ogura Koichi (Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan) ,  Ogura Koichi (Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan) ,  Hosoda Fumie (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Nakamura Hiromi (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Hama Natsuko (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Totoki Yasushi (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Yoshida Akihiko (Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan) ,  Ohashi Shoko (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Rokutan Hirofumi (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Takai Erina (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Yachida Shinichi (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Kawai Akira (Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan) ,  Tanaka Sakae (Department of Orthopaedic Surgery, The University of Tokyo, Tokyo, Japan) ,  Shibata Tatsuhiro (Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan) ,  Shibata Tatsuhiro (Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan)
Material： Genes, Chromosomes & Cancer  (Genes Chromosomes Cancer)
Volume： 56  Issue： 10  Page： 711-718  Publication year： 2017 
JST Material Number： T0902A  ISSN： 1045-2257  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Recurrent H3F3A and IDH2 mutat...

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Thesaurus term： sensitivity ,  Mutation ,  *Recurrence ,  hot spot ,  *osteoclastoma ,  wild type ,  *epigenetics ,  gene ,  DNA ,  molecular genetic phenomenon ,  Exome ,  genome alignment ,  next generation sequencing ,  *Genetic Variation
Semi thesaurus term： *variation(biology) ,  臨床診断 , 【Automatic Indexing@JST】

JST classification (2)： Structure and chemistry of genes  (EC02020U) ,  Research methods in genetics  (EC01020N)

Terms in the title (5)： 骨巨細胞腫 ,  エピジェネティック ,  調節因子 ,  再発 ,  変異