Art

J-GLOBAL ID：201702261065839078   Reference number：17A1827920

Molecular mechanisms of insulin resistance in 2 cases of primary insulin receptor defect-associated diseases

原発性インシュリン受容体欠損関連疾患の2例におけるインスリン抵抗性の分子機構【Powered by NICT】

Author (10)： Tsuji-Hosokawa Atsumi (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Takasawa Kei (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Nomura Risa (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Miyakawa Yuichi (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Numakura Chikahiko (Department of Pediatrics, Yamagata University School of Medicine, Yamagata, Japan) ,  Hijikata Atsushi (Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology, Nagahama, Japan) ,  Shirai Tsuyoshi (Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology, Nagahama, Japan) ,  Ogawa Yoshihiro (Department of Molecular Endocrinology and Metabolism, Tokyo Medical and Dental University, Tokyo, Japan) ,  Kashimada Kenichi (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Morio Tomohiro (Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan)
Material： Pediatric Diabetes
Volume： 18  Issue： 8  Page： 917-924  Publication year： 2017 
JST Material Number： W2717A  ISSN： 1399-543X  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Defects of the ins...

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Thesaurus term： allele ,  *Insulin resistance ,  patient ,  *insulin ,  man ,  lymphocyte ,  Islamic Republic of Iran ,  *insulin receptor ,  phosphorylation ,  function analysis ,  in vitro experiment ,  missense mutation ,  Diabetes Mellitus ,  mRNA expression ,  Genetic Variation ,  *hypoglycemic drug ,  *metabolic drug ,  *carbohydrate metabolic drug ,  *drug
Semi thesaurus term： variation(biology) , 【Automatic Indexing@JST】

Author keywords (4)： congenital insulin resistance ,  insulin receptor ,  insulin-resistant diabetes mellitus with acanthusis nigricans ,  leprechaunism

JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Terms in the title (6)： 原発 ,  インシュリン ,  受容体欠損 ,  疾患 ,  インスリン抵抗性 ,  分子機構