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J-GLOBAL ID：201702262139813114   Reference number：17A1295716

The opposite mechano-response of paxillin phosphorylation between subcellular and whole-cell levels is explained by a minimal model of cell-substrate adhesions

細胞内と全細胞レベルの間でのパキシリンのリン酸化に対する逆の機械反応は,細胞-基質接着最小モデルで説明される

Author (9)： DEGUCHI Shinji (Department of Bioengineering and Robotics, Tohoku University) ,  DEGUCHI Shinji (Division of Bioengineering, Graduate School of Engineering Science, Osaka University) ,  SAITO Akira C. (Department of Bioengineering and Robotics, Tohoku University) ,  MATSUI Tsubasa S. (Department of Bioengineering and Robotics, Tohoku University) ,  MATSUI Tsubasa S. (Division of Bioengineering, Graduate School of Engineering Science, Osaka University) ,  HUANG Wenjing (Department of Bioengineering and Robotics, Tohoku University) ,  HUANG Wenjing (Department of Bioengineering, The University of Tokyo) ,  SATO Masaaki (Department of Bioengineering and Robotics, Tohoku University) ,  SATO Masaaki (Frontier Research Institute for Interdisciplinary Sciences, Tohoku University)
Material： Journal of Biomechanical Science and Engineering (Web)  (J Biomech Sci Eng (Web))
Volume： 12  Issue： 2  Page： 16-00670(J-STAGE)  Publication year： 2017 
JST Material Number： U0024A  ISSN： 1880-9863  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： acceptance(sociology) ,...
Semi thesaurus term： *mechanoception ,...

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Author keywords (6)： Cell-substrate adhesion ,  Focal adhesions ,  Paxillin ,  Cellular contractility ,  Micropatterning ,  Mechanobiology

JST classification (1)： Cell physiology in general  (EF02010S)

Reference (22)：

• Bellis, S.L., Miller, J.T., Turner, C.E., Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J. Biol. Chem., Vol. 270 (1995), pp. 17437-17441.
• Chen, C.S., Mechanotransduction - a field pulling together? J. Cell Sci., Vol. 121 (2008), pp. 3285-3292.
• Deguchi, S., Ohashi, T., Sato, M., Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells. J. Biomech., Vol. 39 (2006), pp. 2603-2610.
• Deguchi, S., Sato, M., Biomechanical properties of actin stress fibers of non-motile cells. Biorheology, Vol. 46 (2009), pp. 93-105.
• Deguchi, S., Matsui, T.S., Iio, K., The position and size of individual focal adhesions are determined by intracellular stress-dependent positive regulation. Cytoskeleton, Vol. 68 (2011), pp. 639-651.

Terms in the title (7)： 全細胞 ,  パキシリン ,  リン酸化 ,  細胞 ,  基質 ,  モデル ,  説明