Art

J-GLOBAL ID：201702263996533803   Reference number：17A0087639

Successful treatment of TAFRO syndrome, a variant type of multicentric Castleman disease with thrombotic microangiopathy, with anti-IL-6 receptor antibody and steroids

血栓性微小血管症のある多中心性Castleman病変異型であるTAFRO症候群の抗IL6受容体抗体とステロイドによる治療の奏功

Author (12)： Fujiwara Shiho (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Mochinaga Hiromi (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Nakata Hirotomo (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Ohshima Koichi (Department of Pathology, Kurume University School of Medicine, Fukuoka, Japan) ,  Matsumoto Masanori (Department of Blood Transfusion Medicine, Nara Medical University, Nara, Japan) ,  Uchiba Mitsuhiro (Department of Blood Transfusion and Cell Therapy, Kumamoto University Hospital, Kumamoto, Japan) ,  Mikami Yoshiki (Department of Surgical Pathology, Kumamoto University Hospital, Kumamoto, Japan) ,  Hata Hiroyuki (Division of Informative Clinical Sciences, Faculty of Medical Sciences, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Okuno Yutaka (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Mitsuya Hiroaki (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Nosaka Kisato (Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan) ,  Nosaka Kisato (Cancer Center of Kumamoto Medical School of Medicine, Kumamoto, Japan)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 103  Issue： 6  Page： 718-723  Publication year： Jun. 2016 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *lymphatic disease ,...
Semi thesaurus term： Multicentric Castleman's disease ,...

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Author keywords (4)： TAFRO syndrome ,  Castleman disease ,  Tocilizumab ,  ADAMTS13

JST classification (1)： Clinical hematology in general  (GK01030Y)

Substance index (1)： Prednisolone

Reference (20)：

• Castleman B, Towne VW. Case records of the Massachusetts General Hospital: case No. 40231. N Engl J Med. 1954;250:1001-5.
• Keller AR, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer. 1972;29:670-83.
• Cronin DM, Warnke RA. Castleman disease: an update on classification and the spectrum of associated lesions. Adv Anat Pathol. 2009;16:236-46.
• Fajgenbaum DC, van Rhee F, Nabel CS. HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy. Blood. 2014;123:2924-33.
• El-Osta HE, Kurzrock R. Castleman’s disease: from basic mechanisms to molecular therapeutics. Oncologist. 2011;16:497-511.

Terms in the title (7)： 血栓性微小血管症 ,  多中心性Castleman病 ,  変異型 ,  TAFRO症候群 ,  抗IL6受容体抗体 ,  ステロイド ,  治療