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J-GLOBAL ID：201702264733079658   Reference number：17A1693179

Amelioration of atopic-like skin conditions in NC/Tnd mice by topical application with distilled Alpinia intermedia Gagnep extracts

蒸留したAlpinia intermedia Gagnep抽出物の局所塗布によりNC/Tndマウスのアトピー様皮膚状態の改善

Author (13)： Amagai Yosuke (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Amagai Yosuke (Research Fellow of the Japan Society for the Promotion of Science, Tokyo, Japan) ,  Katsuta Chihiro (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Nomura Yoshihiro (Applied Protein Chemistry, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Oida Kumiko (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Matsuda Kenshiro (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Jang Hyosun (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Ahn Ginnae (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Hamasaki Tetsuyoshi (Gray Art, Tokyo, Japan) ,  Matsuda Hiroshi (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Matsuda Hiroshi (Laboratory of Veterinary Molecular Pathology and Therapeutics, Tokyo, Japan) ,  Tanaka Akane (Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan) ,  Tanaka Akane (Laboratory of Comparative Animal Medicine, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan)
Material： Journal of Dermatology  (J Dermatol)
Volume： 44  Issue： 11  Page： 1238-1247  Publication year： Nov. 2017 
JST Material Number： W1578A  ISSN： 0385-2407  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： Zingiberaceae ,...
Semi thesaurus term： immunological reaction ,...

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Author keywords (5)： Alpinia intermedia ,  atopic dermatitis ,  NC/Tnd mouse ,  skin care ,  β-pinene

JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic dermatology  (GF01020Y)

Substance index (1)： β-Pinene

Reference (30)：

• Ring J, Alomar A, Bieber T et al. Guidelines for treatment of atopic eczema (atopic dermatitis) part I. J Eur Acad Dermatol Venereol 2012; 26: 1045-1060.
• Schmid-Ott G, Jaeger B, Kapp A, Werfel T. Different expression of cytokine and membrane molecules by circulating lymphocytes on acute mental stress in patients with atopic dermatitis in comparison with healthy controls. J Allergy Clin Immunol 2001; 108: 455-462.
• Palmer CN, Irvine AD, Terron-Kwiatkowski A et al. Common lossof- function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006; 38: 441-446.
• Cork MJ, Danby SG, Vasilopoulos Y et al. Epidermal barrier dysfunction in atopic dermatitis. J Invest Dermatol 2009; 129: 1892- 1908.
• De Benedetto A, Kubo A, Beck LA. Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol 2012; 132: 949-963.

Terms in the title (8)： 蒸留 ,  Alpinia ,  抽出物 ,  局所塗布 ,  NC ,  マウス ,  アトピー ,  皮膚