Art

J-GLOBAL ID：201702269481245718   Reference number：17A0483151

Effects of Candesartan Cilexetil Compared with Amlodipine on Serum Asymmetric Dimethylarginine Levels in the Chronic Stage of Cerebral Infarction: A Preliminary Study

脳梗塞の慢性期における血清中非対称型アルギニンジメチルレベルに対するアミロジピンと比較したカンデサルタンシレキセチルの効果: 予備的研究

Author (9)： Sunami Eiko (Department of Neurology, Shioda Hospital) ,  Sunami Eiko (Department of Internal Medicine, Division of Neurology, Nippon Medical School) ,  Sunami Eiko (Department of Rehabilitation Medicine, Nippon Medical School) ,  Nomura Koichi (Department of Neurology, Shioda Hospital) ,  Nomura Koichi (Department of Internal Medicine, Division of Neurology, Nippon Medical School) ,  Nishiyama Yutaka (Department of Neurology, Shioda Hospital) ,  Nishiyama Yutaka (Department of Internal Medicine, Division of Neurology, Nippon Medical School) ,  Katayama Yasuo (Department of Internal Medicine, Division of Neurology, Nippon Medical School) ,  Katayama Yasuo (Department of Neurology, Tokyo General Hospital)
Material： Journal of Nippon Medical School  (日本医科大学雑誌)
Volume： 83  Issue： 6  Page： 272-276(J-STAGE)  Publication year： 2016 
JST Material Number： F0887A  ISSN： 1345-4676  CODEN： JNMSF5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： Vascular endothelium function test ,...

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Author keywords (5)： asymmetric dimethylarginine ,  cerebral infarction ,  hypertension ,  candesartan cilexetil ,  angiotensin II receptor blocker

JST classification (1)： Drug therapy(=pharmacotherapy)for nervous system diseases  (GN05020Y)

Substance index (3)： NG,NG-Dimethylarginine ,  Amlodipine ,  Candesartan cilexetil

Reference (10)：

• 1. Yoo JH, Lee SC: Elevated levels of plasma homocyst (e) ine and asymmetric dimethylarginine in elderly patients with stroke. Atherosclerosis 2001; 158: 425-430.
• 2. Schrader J, Lüders S, Kulschewski A, Hammersen F, Plate K, Berger J, Zidek W, Dominiak P, Diener HC: Morbidity and mortality after stroke, Eprosartan compared with Nitrendipine for secondary prevention. Stroke 2005; 36: 1218-1226.
• 3. Ito A, Egashira K, Narishige T, Muramatsu K, Kakeshita A: Renin-angiotensin system is involved in the mechanism of increased serum asymmetric dimethylarginine in essential hypertension. Jpn Circ J 2001; 65: 775-778.
• 4. Ono Y, Nakaya Y, Bando S, Soeki T, Ito S, Sata M: Telmisartan decreases plasma levels of asymmetrical dimethyl-L-arginine and improves lipid and glucose metabolism and vascular function. Int Heart J 2009; 50: 73-83.
• 5. Dells C, Schneider MP, John S, Gekle M, Schmieder RE: Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical NG, NG-dimethylarginine in human essential hypertension. Am J Htpertens 2002; 15: 590-593.

Terms in the title (6)： 脳梗塞 ,  慢性期 ,  血清 ,  対称型 ,  カンデサルタンシレキセチル ,  予備的研究