Art

J-GLOBAL ID：201702283031718917   Reference number：17A0559699

Synthesis and Identification of Key Biosynthetic Intermediates for the Formation of the Tricyclic Skeleton of Saxitoxin

サキシトキシンの三環系骨格を生成するためのキー生合成中間体の合成および同定

Author (7)： Tsuchiya Shigeki (Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-0845, Japan) ,  Cho Yuko (Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-0845, Japan) ,  Yoshioka Renpei (Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-0845, Japan) ,  Konoki Keiichi (Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-0845, Japan) ,  Nagasawa Kazuo (Faculty of Technology, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan) ,  Oshima Yasukatsu (Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, 980-8577, Japan) ,  Yotsu-Yamashita Mari (Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-0845, Japan)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 56  Issue： 19  Page： 5327-5331  Publication year： 2017 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： Cyanophyta ,  Dinoflagellida ,  *biosynthesis ,  *synthetic intermediate ,  natural material ,  reaction mechanism ,  metabolic pathway ,  LC-MS analysis ,  *saxitoxin
Semi thesaurus term： cyanobacteria ,  Dinoflagellata ,  Biosynthetic Pathways ,  biosynthesis intermediate ,  natural material ,  Voltage-Gated Sodium Channel Blockers

Author keywords (5)： biosynthesis ,  mass spectrometry ,  natural products ,  reaction mechanisms ,  saxitoxin

JST classification (1)： Purines,pteridines  (CF07105E)

Substance index (3)： (3aS,10aR)-2,6-Diimino-2,3,3aα,4,5,6,8,9-octahydro-1H,10H-pyrrolo[1,2-c]purine-4α-methanol ,  1-[3-[2-Amino-5-(1-hydroxyethyl)-1H-imidazole-4-yl]propyl]guanidine ,  (+)-Saxitoxin

Terms in the title (6)： サキシトキシン ,  三環 ,  骨格 ,  キー ,  生合成中間体 ,  同定