Art

J-GLOBAL ID：201702283101710827   Reference number：17A0657500

Simultaneous and rapid determination of gefitinib, erlotinib and afatinib plasma levels using liquid chromatography/tandem mass spectrometry in patients with non-small-cell lung cancer

肺非小細胞癌患者における液体クロマトグラフィー/タンデム質量分析を用いたゲフィチニブ,エルロチニブとアファチニブ血しょう中濃度の同時迅速定量【Powered by NICT】

Author (14)： Hayashi Hideki (Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan) ,  Hayashi Hideki (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Kita Yutaro (Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan) ,  Iihara Hirotoshi (Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan) ,  Iihara Hirotoshi (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Yanase Koumei (Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Ohno Yasushi (Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Hirose Chiemi (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Yamada Maya (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Todoroki Kenichiro (Department of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan) ,  Kitaichi Kiyoyuki (Laboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu, Japan) ,  Minatoguchi Shinya (Second Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Itoh Yoshinori (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Sugiyama Tadashi (Laboratory of Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan)
Material： Biomedical Chromatography  (BMC)
Volume： 30  Issue： 7  Page： 1150-1154  Publication year： Jul. 2016 
JST Material Number： E0166C  ISSN： 0269-3879  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： A simultaneous, selective, sen...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A0657500&from=J-GLOBAL&jstjournalNo=E0166C") }}

Thesaurus term： human ,  oral administration ,  therapeutic drug monitoring ,  calibration curve ,  Plasma ,  *plasma concentration ,  mobile phase ,  *patient ,  electrospray ionization ,  extraction ,  *rapid analysis ,  simultaneous determination ,  high performance liquid chromatography ,  *liquid chromatography-tandem mass spectrometry ,  enzyme inhibitor
Semi thesaurus term： *LC/MS/MS , 【Automatic Indexing@JST】

Author keywords (5)： gefitinib ,  erlotinib ,  afatinib ,  LC-MS/MS ,  therapeutic drug monitoring

JST classification (2)： Basic biopharmacy  (GY01021U) ,  Miscellaneous analytical methods of organic compounds  (CC08034J)

Substance index (1)： Erlotinib

Terms in the title (9)： 肺非小細胞癌 ,  患者 ,  液体クロマトグラフィー ,  タンデム質量分析 ,  ゲフィチニブ ,  エルロチニブ ,  アファチニブ ,  血しょう中濃度 ,  迅速定量