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J-GLOBAL ID：201702289342253316   Reference number：17A1824846

Ectopic expression of the transcription factor MafB in basal keratinocytes induces hyperproliferation and perturbs epidermal homeostasis

基底ケラチン細胞における転写因子MafBの異所性発現は過剰増殖を誘導し,表皮の恒常性を混乱させる【Powered by NICT】

Author (7)： Miyai Masashi (Laboratory of Molecular and Developmental Biology, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan) ,  Tsunekage Yukino (Laboratory of Molecular Medical Bioscience, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan) ,  Saito Michiko (Laboratory of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan) ,  Kohno Kenji (Laboratory of Molecular and Cell Genetics, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan) ,  Takahashi Kenzo (Department of Dermatology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan) ,  Kataoka Kohsuke (Laboratory of Molecular and Developmental Biology, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Ikoma, Japan) ,  Kataoka Kohsuke (Laboratory of Molecular Medical Bioscience, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan)
Material： Experimental Dermatology
Volume： 26  Issue： 11  Page： 1039-1045  Publication year： 2017 
JST Material Number： W2573A  ISSN： 0906-6705  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Mammalian epidermis is compose...

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Thesaurus term： keratinization ,  *transcription factor ,  differentiation(biology) ,  cell proliferation ,  homeostasis ,  *keratin ,  promoter(genetics) ,  basal cell ,  transgenic mouse ,  skin disease ,  *keratinocyte ,  morphology ,  mitosis
Semi thesaurus term： 悪性腫瘍 ,  *MafB転写因子 , 【Automatic Indexing@JST】

Author keywords (5)： cell proliferation ,  epidermal homeostasis ,  keratinocyte differentiation ,  MafB ,  transcription factor

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (10)： 基底 ,  ケラチン細胞 ,  転写因子 ,  MafB ,  異所性発現 ,  増殖 ,  誘導 ,  表皮 ,  恒常性 ,  混乱